Prion strains and amyloid polymorphism influence phenotypic variation.

Prion strains and amyloid polymorphism influence phenotypic variation.

Bibliographic Details
Main Authors:	Kevin C Stein, Heather L True
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-09-01
Series:	PLoS Pathogens
Online Access:	http://europepmc.org/articles/PMC4154852?pdf=render

Similar Items

Spontaneous variants of the [RNQ+] prion in yeast demonstrate the extensive conformational diversity possible with prion proteins.
by: Vincent J Huang, et al.
Published: (2013-01-01)

Regulation of the Hsp104 middle domain activity is critical for yeast prion propagation.
by: Jennifer E Dulle, et al.
Published: (2014-01-01)

Physical Properties of Polymorphic Yeast Prion Amyloid Fibers
by: Castro, Carlos E., et al.
Published: (2015)

Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma
by: Martin L. Daus
Published: (2016-01-01)

Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics
by: Frederick, Kendra K., et al.
Published: (2016)

Differential Accumulation of Misfolded Prion Strains in Natural Hosts of Prion Diseases
by: Zoe J. Lambert, et al.
Published: (2021-12-01)

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression
by: Alejandro Ruiz-Riquelme, et al.
Published: (2018-04-01)

Mechanisms of Strain Diversity of Disease-Associated in-Register Parallel β-Sheet Amyloids and Implications About Prion Strains
by: Yuzuru Taguchi, et al.
Published: (2019-01-01)

Comparing the Folds of Prions and Other Pathogenic Amyloids
by: José Miguel Flores-Fernández, et al.
Published: (2018-05-01)

Amyloidosis-history and development, emphasis on insulin and prion amyloids
by: Sanjay Kisan Metkar, et al.
Published: (2024-03-01)

Prion replication environment defines the fate of prion strain adaptation.
by: Elizaveta Katorcha, et al.
Published: (2018-06-01)

Modeling amyloid-beta as homogeneous dodecamers and in complex with cellular prion protein.
by: Steven L Gallion
Published: (2012-01-01)

Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype.
by: Isobel J Whitehouse, et al.
Published: (2016-01-01)

Kinetics of amyloid aggregation: a study of the GNNQQNY prion sequence.
by: Jessica Nasica-Labouze, et al.
Published: (2012-01-01)

Prions, prionoid complexes and amyloids: the bad, the good and something in between
by: Iva Hafner-Bratkovič
Published: (2017-04-01)

Evidence for preexisting prion substrain diversity in a biologically cloned prion strain.
by: Tess Gunnels, et al.
Published: (2023-09-01)

Structural Variations of Prions and Prion-like Proteins Associated with Neurodegeneration
by: Carter Sky Christensen, et al.
Published: (2024-06-01)

Prions, protein homeostasis, and phenotypic diversity
by: Lindquist, Susan, et al.
Published: (2010)

Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring.
by: Bruce Chesebro, et al.
Published: (2010-03-01)

Effects of Pulsed Electric Fields on Yeast with Prions and the Structure of Amyloid Fibrils
by: Justina Jurgelevičiūtė, et al.
Published: (2021-03-01)

The physical dimensions of amyloid aggregates control their infective potential as prion particles
by: Ricardo Marchante, et al.
Published: (2017-09-01)

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.
by: Baskakov, I, et al.
Published: (2005)

Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity
by: Reymer, Anna, et al.
Published: (2015)

Prion Protein Misfolding, Strains, and Neurotoxicity: An Update from Studies on Mammalian Prions
by: Ilaria Poggiolini, et al.
Published: (2013-01-01)

Polymorphism of prion protein gene (PRNP) in Nigerian sheep
by: Adeniyi C. Adeola, et al.
Published: (2023-12-01)

The first report of prion protein gene sequences in Dybowski’s frog and the American bullfrog: high amyloid propensity of the frog prion protein
by: Sae-Young Won, et al.
Published: (2024-10-01)

Strain-Specific Targeting and Destruction of Cells by Prions
by: Sara M. Simmons, et al.
Published: (2024-01-01)

Genetic prion disease: D178N with 129MV disease modifying polymorphism—a clinical phenotype
by: Dominic Thyagarajan, et al.
Published: (2020-12-01)

A micellar on-pathway intermediate step explains the kinetics of prion amyloid formation.
by: Erwan Hingant, et al.
Published: (2014-08-01)

Imaging of Brain Prion Protein Amyloid in Patients with Gertstmann-Sträussler- Scheinker Disease
by: Thuy A. Tran, et al.
Published: (2011-12-01)

Curcumin Reduces Amyloid Fibrillation of Prion Protein and Decreases Reactive Oxidative Stress
by: Raymond Chung, et al.
Published: (2013-07-01)

Biochemical, Cell Biological, and Genetic Assays to Analyze Amyloid and Prion Aggregation in Yeast
by: Alberti, Simon, et al.
Published: (2011)

Polymorphisms in the Prion Protein Gene of cattle breeds from Brazil
by: Cristiane C. Sanches, et al.

Novel polymorphisms in the prion protein gene (PRNP) and stability of the resultant prion protein in different horse breeds
by: Diego Sola, et al.
Published: (2023-10-01)

Prion protein expression and processing in human mononuclear cells: the impact of the codon 129 prion gene polymorphism.
by: Christiane Segarra, et al.
Published: (2009-06-01)

Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein
by: Ryan Myers, et al.
Published: (2020-08-01)

Prion Strains Differ in Susceptibility to Photodynamic Oxidation
by: Marie Kostelanska, et al.
Published: (2022-01-01)

Biochemical Characterization of Prion Strains in Bank Voles
by: Romolo Nonno, et al.
Published: (2013-07-01)

Synthetic prions with novel strain-specified properties.
by: Fabio Moda, et al.
Published: (2015-12-01)

Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains
by: Forrest Hoyt, et al.
Published: (2022-07-01)