Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Pre...

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Main Authors: Chang-Zhang Chai, Ue-Cheung Ho, Lu-Ting Kuo
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/13/10943
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author Chang-Zhang Chai
Ue-Cheung Ho
Lu-Ting Kuo
author_facet Chang-Zhang Chai
Ue-Cheung Ho
Lu-Ting Kuo
author_sort Chang-Zhang Chai
collection DOAJ
description Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.
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spelling doaj.art-da068c141b22487199d595e75ede77e92023-11-18T16:45:46ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-06-0124131094310.3390/ijms241310943Systemic Inflammation after Aneurysmal Subarachnoid HemorrhageChang-Zhang Chai0Ue-Cheung Ho1Lu-Ting Kuo2Department of Medical Education, National Taiwan University, School of Medicine, Taipei 100, TaiwanDivision of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin 640, TaiwanDivision of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin 640, TaiwanAneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.https://www.mdpi.com/1422-0067/24/13/10943cerebral aneurysmsubarachnoid hemorrhagesystemic inflammation
spellingShingle Chang-Zhang Chai
Ue-Cheung Ho
Lu-Ting Kuo
Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
International Journal of Molecular Sciences
cerebral aneurysm
subarachnoid hemorrhage
systemic inflammation
title Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
title_full Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
title_fullStr Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
title_full_unstemmed Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
title_short Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
title_sort systemic inflammation after aneurysmal subarachnoid hemorrhage
topic cerebral aneurysm
subarachnoid hemorrhage
systemic inflammation
url https://www.mdpi.com/1422-0067/24/13/10943
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AT uecheungho systemicinflammationafteraneurysmalsubarachnoidhemorrhage
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