Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Pre...
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Format: | Article |
Language: | English |
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MDPI AG
2023-06-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/24/13/10943 |
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author | Chang-Zhang Chai Ue-Cheung Ho Lu-Ting Kuo |
author_facet | Chang-Zhang Chai Ue-Cheung Ho Lu-Ting Kuo |
author_sort | Chang-Zhang Chai |
collection | DOAJ |
description | Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system. |
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format | Article |
id | doaj.art-da068c141b22487199d595e75ede77e9 |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-11T01:39:29Z |
publishDate | 2023-06-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-da068c141b22487199d595e75ede77e92023-11-18T16:45:46ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-06-0124131094310.3390/ijms241310943Systemic Inflammation after Aneurysmal Subarachnoid HemorrhageChang-Zhang Chai0Ue-Cheung Ho1Lu-Ting Kuo2Department of Medical Education, National Taiwan University, School of Medicine, Taipei 100, TaiwanDivision of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin 640, TaiwanDivision of Neurosurgery, Department of Surgery, National Taiwan University Hospital Yunlin Branch, Yunlin 640, TaiwanAneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.https://www.mdpi.com/1422-0067/24/13/10943cerebral aneurysmsubarachnoid hemorrhagesystemic inflammation |
spellingShingle | Chang-Zhang Chai Ue-Cheung Ho Lu-Ting Kuo Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage International Journal of Molecular Sciences cerebral aneurysm subarachnoid hemorrhage systemic inflammation |
title | Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage |
title_full | Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage |
title_fullStr | Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage |
title_full_unstemmed | Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage |
title_short | Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage |
title_sort | systemic inflammation after aneurysmal subarachnoid hemorrhage |
topic | cerebral aneurysm subarachnoid hemorrhage systemic inflammation |
url | https://www.mdpi.com/1422-0067/24/13/10943 |
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