Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice

Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice

Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse models of AD. However, whether and how aerobic exercise can...

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Bibliographic Details
Main Authors: Dan Qiu, Shi Zhou, James Donnelly, Dongdong Xia, Li Zhao
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Experimental Gerontology
Subjects:
Aerobic exercise
AD model
Myelin sheath
Oligodendrocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523002140

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