Iron Imaging as a Diagnostic Tool for Parkinson's Disease: A Systematic Review and Meta-Analysis

Iron Imaging as a Diagnostic Tool for Parkinson's Disease: A Systematic Review and Meta-Analysis

Background: Parkinson's disease (PD) is a progressive neurodegenerative disease whose main neuropathological feature is the loss of dopaminergic neurons of the substantia nigra (SN). There is also an increase in iron content in the SN in postmortem and imaging studies using iron-sensitive MRI t...

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Bibliographic Details
Main Authors: Nadya Pyatigorskaya, Clara B. Sanz-Morère, Rahul Gaurav, Emma Biondetti, Romain Valabregue, Mathieu Santin, Lydia Yahia-Cherif, Stéphane Lehéricy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neurology
Subjects:
substantia nigra
iron
Parkinson's disease
QSM
SWI
R2*
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00366/full

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