Interpreting clinical trial outcomes complicated by placebo response with an assessment of false-negative and true-negative clinical trials in depression using propensity-weighting

Abstract The objective of this study was to evaluate the performances of the propensity score weighted (PSW) methodology in a post-hoc re-analysis of a failed and a negative RCTs in depressive disorders. The conventional study designs, randomizations, and statistical approaches do not account for th...

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Bibliographic Details
Main Authors: Roberto Gomeni, Seth Hopkins, Françoise Bressolle-Gomeni, Maurizio Fava
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02685-y

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