Transcriptome Analysis and Single-Cell Sequencing Analysis Constructed the Ubiquitination-Related Signature in Glioma and Identified USP4 as a Novel Biomarker

Transcriptome Analysis and Single-Cell Sequencing Analysis Constructed the Ubiquitination-Related Signature in Glioma and Identified USP4 as a Novel Biomarker

BackgroundGlioma, the most frequent malignant tumor of the neurological system, has a poor prognosis and treatment problems. Glioma’s tumor microenvironment is also little known.MethodsWe downloaded glioma data from the TCGA database. The patients in the TCGA database were split into two groups, one...

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Bibliographic Details
Main Authors: Qikai Tang, Zhengxin Chen, Jiaheng Xie, Chuangqi Mo, Jiacheng Lu, Qixiang Zhang, Zhangjie Wang, Wei Wu, Huibo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
glioma
ubiquitination
bioinformatics
signature
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.915709/full

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