Sustainable Synthesis, Antiproliferative and Acetylcholinesterase Inhibition of 1,4- and 1,2-Naphthoquinone Derivatives

Sustainable Synthesis, Antiproliferative and Acetylcholinesterase Inhibition of 1,4- and 1,2-Naphthoquinone Derivatives

This work describes the design, sustainable synthesis, evaluation of electrochemical and biological properties against HepG2 cell lines, and AChE enzymes of different substituted derivatives of 1,4- and 1,2-naphthoquinones (NQ). A microwave-assisted protocol was optimized with success for the synthe...

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Bibliographic Details
Main Authors: Rafaela G. Cabral, Gonçalo Viegas, Rita Pacheco, Ana Catarina Sousa, Maria Paula Robalo
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
naphthoquinones
electrochemistry behavior
acetylcholinesterase inhibitory activity
cytotoxic activity
biological activity
Online Access:https://www.mdpi.com/1420-3049/28/3/1232

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