Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors
Tomato spotted wilt virus (TSWV) is the type member of the genus <i>Orthotospovirus</i> in the family <i>Tospoviridae</i> and order Bunyavirales. TSWV, transmitted by several species of thrips, causes significant disease losses to agronomic and horticultural crops worldwide,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/3/320 |
| _version_ | 1827698233725419520 |
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| author | Alexander Nilon Karl Robinson Hanu R. Pappu Neena Mitter |
| author_facet | Alexander Nilon Karl Robinson Hanu R. Pappu Neena Mitter |
| author_sort | Alexander Nilon |
| collection | DOAJ |
| description | Tomato spotted wilt virus (TSWV) is the type member of the genus <i>Orthotospovirus</i> in the family <i>Tospoviridae</i> and order Bunyavirales. TSWV, transmitted by several species of thrips, causes significant disease losses to agronomic and horticultural crops worldwide, impacting both the yield and quality of the produce. Management strategies include growing virus-resistant cultivars, cultural practices, and managing thrips vectors through pesticide application. However, numerous studies have reported that TSWV isolates can overcome host-plant resistance, while thrips are developing resistance to pesticides that were once effective. RNA interference (RNAi) offers a means of host defence by using double-stranded (ds) RNA to initiate gene silencing against invading viruses. However, adoption of this approach requires production and use of transgenic plants and thus limits the practical application of RNAi against TSWV and other viruses. To fully utilize the potential of RNAi for virus management at the field level, new and novel approaches are needed. In this review, we summarize RNAi and highlight the potential of topical or exogenous application of RNAi triggers for managing TSWV and thrips vectors. |
| first_indexed | 2024-03-10T13:25:36Z |
| format | Article |
| id | doaj.art-da1951395e8643d79cb23777ad4af869 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T13:25:36Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-da1951395e8643d79cb23777ad4af8692023-11-21T09:40:46ZengMDPI AGPathogens2076-08172021-03-0110332010.3390/pathogens10030320Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips VectorsAlexander Nilon0Karl Robinson1Hanu R. Pappu2Neena Mitter3Centre for Horticultural Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4067, AustraliaCentre for Horticultural Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4067, AustraliaDepartment of Plant Pathology, Washington State University, Pullman, WA 99164-6430, USACentre for Horticultural Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4067, AustraliaTomato spotted wilt virus (TSWV) is the type member of the genus <i>Orthotospovirus</i> in the family <i>Tospoviridae</i> and order Bunyavirales. TSWV, transmitted by several species of thrips, causes significant disease losses to agronomic and horticultural crops worldwide, impacting both the yield and quality of the produce. Management strategies include growing virus-resistant cultivars, cultural practices, and managing thrips vectors through pesticide application. However, numerous studies have reported that TSWV isolates can overcome host-plant resistance, while thrips are developing resistance to pesticides that were once effective. RNA interference (RNAi) offers a means of host defence by using double-stranded (ds) RNA to initiate gene silencing against invading viruses. However, adoption of this approach requires production and use of transgenic plants and thus limits the practical application of RNAi against TSWV and other viruses. To fully utilize the potential of RNAi for virus management at the field level, new and novel approaches are needed. In this review, we summarize RNAi and highlight the potential of topical or exogenous application of RNAi triggers for managing TSWV and thrips vectors.https://www.mdpi.com/2076-0817/10/3/320tomato spotted wilt virusRNA interferencethripsdisease managementtospovirusesdouble-stranded RNA |
| spellingShingle | Alexander Nilon Karl Robinson Hanu R. Pappu Neena Mitter Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors Pathogens tomato spotted wilt virus RNA interference thrips disease management tospoviruses double-stranded RNA |
| title | Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors |
| title_full | Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors |
| title_fullStr | Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors |
| title_full_unstemmed | Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors |
| title_short | Current Status and Potential of RNA Interference for the Management of Tomato Spotted Wilt Virus and Thrips Vectors |
| title_sort | current status and potential of rna interference for the management of tomato spotted wilt virus and thrips vectors |
| topic | tomato spotted wilt virus RNA interference thrips disease management tospoviruses double-stranded RNA |
| url | https://www.mdpi.com/2076-0817/10/3/320 |
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