Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) is one of the common rheumatic diseases in pediatrics. Persistent synovitis and joint pain cause reduced range of motion, deformity and gait interruption, which are important reasons for children's disability and a decline in their quality of life. Rheumatolo...

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Main Authors: Sha Li, Wei Zhang, Yan Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.822009/full
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author Sha Li
Wei Zhang
Yan Lin
author_facet Sha Li
Wei Zhang
Yan Lin
author_sort Sha Li
collection DOAJ
description Juvenile idiopathic arthritis (JIA) is one of the common rheumatic diseases in pediatrics. Persistent synovitis and joint pain cause reduced range of motion, deformity and gait interruption, which are important reasons for children's disability and a decline in their quality of life. Rheumatology experts have explored good treatment strategies, among which intra-articular corticosteroid injections (IACIs) targeting joints can greatly reduce these systemic adverse reactions while still obtaining local anti-inflammatory effects. Local inhibition of synovitis by the use of steroid hormones in a joint cavity can avoid or reduce adverse reactions of systemic therapy, prevent or treat leg length variance and joint contracture, solve Baker's cyst, improve tenosynovitis, promote physical therapy and rehabilitation, make gait change smoothly, relieve pain, and restore joint function. Given the importance of IACIs in treating JIA, this paper reviewed the case selection, drug injection, dose selection, current anesthesia and injection techniques, the efficacy, recurrence, and influencing factors of IACIs, the management of physiotherapy intervention post-injection, the application of ultrasound guidance and the safety and complications of IACIs in children with JIA. This study aims to guide the use of IACIs for the best approach throughout the review.
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spelling doaj.art-da1a6626511b4f4dbfd7c2cfa01081c82022-12-21T18:20:03ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-03-011010.3389/fped.2022.822009822009Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic ArthritisSha Li0Wei Zhang1Yan Lin2Department of Rheumatology, The Affiliated Women's and Children's Hospital, School of Medicine UESTC, Chengdu Women and Children's Central Hospital, Chengdu, ChinaDepartment of Rheumatology, The Affiliated Women's and Children's Hospital, School of Medicine UESTC, Chengdu Women and Children's Central Hospital, Chengdu, ChinaDepartment of Outpatient, The Affiliated Women's and Children's Hospital, School of Medicine UESTC, Chengdu Women and Children's Central Hospital, Chengdu, ChinaJuvenile idiopathic arthritis (JIA) is one of the common rheumatic diseases in pediatrics. Persistent synovitis and joint pain cause reduced range of motion, deformity and gait interruption, which are important reasons for children's disability and a decline in their quality of life. Rheumatology experts have explored good treatment strategies, among which intra-articular corticosteroid injections (IACIs) targeting joints can greatly reduce these systemic adverse reactions while still obtaining local anti-inflammatory effects. Local inhibition of synovitis by the use of steroid hormones in a joint cavity can avoid or reduce adverse reactions of systemic therapy, prevent or treat leg length variance and joint contracture, solve Baker's cyst, improve tenosynovitis, promote physical therapy and rehabilitation, make gait change smoothly, relieve pain, and restore joint function. Given the importance of IACIs in treating JIA, this paper reviewed the case selection, drug injection, dose selection, current anesthesia and injection techniques, the efficacy, recurrence, and influencing factors of IACIs, the management of physiotherapy intervention post-injection, the application of ultrasound guidance and the safety and complications of IACIs in children with JIA. This study aims to guide the use of IACIs for the best approach throughout the review.https://www.frontiersin.org/articles/10.3389/fped.2022.822009/fullcorticosteroidintra-articular injectionjuvenile idiopathic arthritisjuvenileapplication
spellingShingle Sha Li
Wei Zhang
Yan Lin
Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
Frontiers in Pediatrics
corticosteroid
intra-articular injection
juvenile idiopathic arthritis
juvenile
application
title Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
title_full Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
title_fullStr Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
title_full_unstemmed Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
title_short Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
title_sort application of intra articular corticosteroid injection in juvenile idiopathic arthritis
topic corticosteroid
intra-articular injection
juvenile idiopathic arthritis
juvenile
application
url https://www.frontiersin.org/articles/10.3389/fped.2022.822009/full
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