MRI Visual Ratings of Brain Atrophy and White Matter Hyperintensities across the Spectrum of Cognitive Decline Are Differently Affected by Age and Diagnosis

MRI Visual Ratings of Brain Atrophy and White Matter Hyperintensities across the Spectrum of Cognitive Decline Are Differently Affected by Age and Diagnosis

Aim: To assess the associations of age and diagnosis with visual ratings of medial temporal lobe atrophy (MTA), parietal atrophy (PA), global cortical atrophy (GCA), and white matter hyperintensities (WMH) and to investigate their clinical value in a large memory clinic cohort.Methods: We included 2...

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Bibliographic Details
Main Authors: Hanneke F. M. Rhodius-Meester, Marije R. Benedictus, Mike P. Wattjes, Frederik Barkhof, Philip Scheltens, Majon Muller, Wiesje M. van der Flier
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
mild cognitive impairment (MCI)
MRI
prognosis
diagnostic test assessment
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00117/full

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