Binding characteristics of [3H]-irbesartan to human recombinant angiotensin type 1 receptors

The aim of the present work was to investigate the binding properties of the selective AT 1 -receptor antagonist irbesartan to human AT 1 -receptors by direct radioligand binding. For this purpose the specific binding of [ 3 H]-irbesartan to intact Chinese Hamster Ovary (CHO) cells expressing human...

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Bibliographic Details
Main Authors: Patrick ML Vanderheyden, Ilse Verheijen, Frederik LP Fierens, Jean-Paul De Backer, Georges Vauquelin
Format: Article
Language:English
Published: SAGE Publications 2000-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2000.020

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