Pre-clinical study of protective potency of candidate recombinant live pertussis vaccine for intranasal administration

Pre-clinical study of protective potency of candidate recombinant live pertussis vaccine for intranasal administration

The aim of present research is studying of protective potency of candidate recombinant live pertussis vaccine (RLPV) for intranasal administration.Materials and methods. Two methods of protective potency assessment, based on mice survival estimating, were used: after intracerebral administration of...

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Bibliographic Details
Main Authors: L. N. Sinyashina, E. G. Semin, A. Yu. Medkova, R. A. Syundyukova, G. I. Karataev
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2019-08-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
live pertussis vaccine
intranasal administration
protective potency
survival
Online Access:https://microbiol.elpub.ru/jour/article/view/365

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