A single acute hepatotoxic dose of CCl4 causes oxidative stress in the rat brain

A single acute hepatotoxic dose of CCl4 causes oxidative stress in the rat brain

Carbon tetrachloride (CCl4), a hepatotoxic agent is widely used to study the toxic mechanisms in experimental animals. We have investigated whether oxidative stress is induced in the brain at a single hepatotoxic dosage (1 ml/kg bw) of CCl4. Increased lipid peroxidation (LPO), protein carbonyls (PC)...

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Bibliographic Details
Main Authors:	K.R. Ritesh, A. Suganya, H.V. Dileepkumar, Y. Rajashekar, T. Shivanandappa
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Series:	Toxicology Reports
Subjects:	Carbon tetrachloride GSH ROS Neurotoxicity Oxidative stress Antioxidant enzymes
Online Access:	http://www.sciencedirect.com/science/article/pii/S221475001530007X

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