Alternative Splicing in the Regulatory Circuit of Plant Temperature Response
As sessile organisms, plants have evolved complex mechanisms to rapidly respond to ever-changing ambient temperatures. Temperature response in plants is modulated by a multilayer regulatory network, including transcriptional and post-transcriptional regulations. Alternative splicing (AS) is an essen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/4/3878 |
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| author | Rong Xue Ruirui Mo Dongkai Cui Wencong Cheng Haoyu Wang Jinxia Qin Zhenshan Liu |
| author_facet | Rong Xue Ruirui Mo Dongkai Cui Wencong Cheng Haoyu Wang Jinxia Qin Zhenshan Liu |
| author_sort | Rong Xue |
| collection | DOAJ |
| description | As sessile organisms, plants have evolved complex mechanisms to rapidly respond to ever-changing ambient temperatures. Temperature response in plants is modulated by a multilayer regulatory network, including transcriptional and post-transcriptional regulations. Alternative splicing (AS) is an essential post-transcriptional regulatory mechanism. Extensive studies have confirmed its key role in plant temperature response, from adjustment to diurnal and seasonal temperature changes to response to extreme temperatures, which has been well documented by previous reviews. As a key node in the temperature response regulatory network, AS can be modulated by various upstream regulations, such as chromatin modification, transcription rate, RNA binding proteins, RNA structure and RNA modifications. Meanwhile, a number of downstream mechanisms are affected by AS, such as nonsense-mediated mRNA decay (NMD) pathway, translation efficiency and production of different protein variants. In this review, we focus on the links between splicing regulation and other mechanisms in plant temperature response. Recent advances regarding how AS is regulated and the following consequences in gene functional modulation in plant temperature response will be discussed. Substantial evidence suggests that a multilayer regulatory network integrating AS in plant temperature response has been unveiled. |
| first_indexed | 2024-03-11T08:42:21Z |
| format | Article |
| id | doaj.art-da2a414597ce40cfac80cdc6b9206196 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T08:42:21Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
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| series | International Journal of Molecular Sciences |
| spelling | doaj.art-da2a414597ce40cfac80cdc6b92061962023-11-16T21:06:20ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-02-01244387810.3390/ijms24043878Alternative Splicing in the Regulatory Circuit of Plant Temperature ResponseRong Xue0Ruirui Mo1Dongkai Cui2Wencong Cheng3Haoyu Wang4Jinxia Qin5Zhenshan Liu6State Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A&F University, Xi’an 712100, ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, Institute of Future Agriculture, Northwest A&F University, Xi’an 712100, ChinaAs sessile organisms, plants have evolved complex mechanisms to rapidly respond to ever-changing ambient temperatures. Temperature response in plants is modulated by a multilayer regulatory network, including transcriptional and post-transcriptional regulations. Alternative splicing (AS) is an essential post-transcriptional regulatory mechanism. Extensive studies have confirmed its key role in plant temperature response, from adjustment to diurnal and seasonal temperature changes to response to extreme temperatures, which has been well documented by previous reviews. As a key node in the temperature response regulatory network, AS can be modulated by various upstream regulations, such as chromatin modification, transcription rate, RNA binding proteins, RNA structure and RNA modifications. Meanwhile, a number of downstream mechanisms are affected by AS, such as nonsense-mediated mRNA decay (NMD) pathway, translation efficiency and production of different protein variants. In this review, we focus on the links between splicing regulation and other mechanisms in plant temperature response. Recent advances regarding how AS is regulated and the following consequences in gene functional modulation in plant temperature response will be discussed. Substantial evidence suggests that a multilayer regulatory network integrating AS in plant temperature response has been unveiled.https://www.mdpi.com/1422-0067/24/4/3878splicing isoformstemperature changeregulatory networkheat stresscold stress |
| spellingShingle | Rong Xue Ruirui Mo Dongkai Cui Wencong Cheng Haoyu Wang Jinxia Qin Zhenshan Liu Alternative Splicing in the Regulatory Circuit of Plant Temperature Response International Journal of Molecular Sciences splicing isoforms temperature change regulatory network heat stress cold stress |
| title | Alternative Splicing in the Regulatory Circuit of Plant Temperature Response |
| title_full | Alternative Splicing in the Regulatory Circuit of Plant Temperature Response |
| title_fullStr | Alternative Splicing in the Regulatory Circuit of Plant Temperature Response |
| title_full_unstemmed | Alternative Splicing in the Regulatory Circuit of Plant Temperature Response |
| title_short | Alternative Splicing in the Regulatory Circuit of Plant Temperature Response |
| title_sort | alternative splicing in the regulatory circuit of plant temperature response |
| topic | splicing isoforms temperature change regulatory network heat stress cold stress |
| url | https://www.mdpi.com/1422-0067/24/4/3878 |
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