Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion
Background: With the prevalence of assisted reproductive technology (ART), the incidence of ectopic pregnancy (EP) is increasing, especially in patients with salpingectomy or proximal tubal occlusion. Methods: A total of 11,609 women who were undergoing ART and had undergone salpingectomy or proxima...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2022-08-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/49/9/10.31083/j.ceog4909196 |
| _version_ | 1798001231219654656 |
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| author | Caihe Wen Yuan Zhang Xinru Xia Xiang Ma Yundong Mao Dao Wu Wang Jiayin Liu |
| author_facet | Caihe Wen Yuan Zhang Xinru Xia Xiang Ma Yundong Mao Dao Wu Wang Jiayin Liu |
| author_sort | Caihe Wen |
| collection | DOAJ |
| description | Background: With the prevalence of assisted reproductive technology (ART), the incidence of ectopic pregnancy (EP) is increasing, especially in patients with salpingectomy or proximal tubal occlusion. Methods: A total of 11,609 women who were undergoing ART and had undergone salpingectomy or proximal tubal occlusion, and 5388 women who achieved a clinical pregnancy were included in the study. Statistical analysis was used to determine whether the number of embryos transferred was associated with EP. Results: Both the number of embryos transferred and the day of embryo transfer differed significantly between those with and without EP (p < 0.05), while the number of embryos transferred was associated with interstitial pregnancy (IP) (p < 0.05) in those undergoing frozen-thawed embryo transfer (ET) cycles. Following multivariate modeling, the odds of having an EP in women undergoing frozen-thawed ET cycles increased with the number of embryos transferred (odds ratio [OR] 2.003, 95% confidence interval [95% CI] 1.036–3.876). Conclusions: The embryo transfer number was considered a risk factor for EP in patients undergoing frozen-thawed ET who had undergone salpingectomy or proximal tubal occlusion. |
| first_indexed | 2024-04-11T11:32:56Z |
| format | Article |
| id | doaj.art-da2ca787410c451ca6871359edba6ae7 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-04-11T11:32:56Z |
| publishDate | 2022-08-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-da2ca787410c451ca6871359edba6ae72022-12-22T04:26:04ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-08-0149919610.31083/j.ceog4909196S0390-6663(22)01779-1Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal OcclusionCaihe Wen0Yuan Zhang1Xinru Xia2Xiang Ma3Yundong Mao4Dao Wu Wang5Jiayin Liu6State Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaState Key Laboratory of Reproductive Medicine, the Center for Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, ChinaBackground: With the prevalence of assisted reproductive technology (ART), the incidence of ectopic pregnancy (EP) is increasing, especially in patients with salpingectomy or proximal tubal occlusion. Methods: A total of 11,609 women who were undergoing ART and had undergone salpingectomy or proximal tubal occlusion, and 5388 women who achieved a clinical pregnancy were included in the study. Statistical analysis was used to determine whether the number of embryos transferred was associated with EP. Results: Both the number of embryos transferred and the day of embryo transfer differed significantly between those with and without EP (p < 0.05), while the number of embryos transferred was associated with interstitial pregnancy (IP) (p < 0.05) in those undergoing frozen-thawed embryo transfer (ET) cycles. Following multivariate modeling, the odds of having an EP in women undergoing frozen-thawed ET cycles increased with the number of embryos transferred (odds ratio [OR] 2.003, 95% confidence interval [95% CI] 1.036–3.876). Conclusions: The embryo transfer number was considered a risk factor for EP in patients undergoing frozen-thawed ET who had undergone salpingectomy or proximal tubal occlusion.https://www.imrpress.com/journal/CEOG/49/9/10.31083/j.ceog4909196interstitial pregnancyectopic pregnancyivf-etnumbers of embryos transferreddays of embryo transfer |
| spellingShingle | Caihe Wen Yuan Zhang Xinru Xia Xiang Ma Yundong Mao Dao Wu Wang Jiayin Liu Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion Clinical and Experimental Obstetrics & Gynecology interstitial pregnancy ectopic pregnancy ivf-et numbers of embryos transferred days of embryo transfer |
| title | Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion |
| title_full | Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion |
| title_fullStr | Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion |
| title_full_unstemmed | Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion |
| title_short | Association of the Number of Embryos Transferred with Ectopic Pregnancy after Embryo Transfer in Patients with Salpingectomy or Proximal Tubal Occlusion |
| title_sort | association of the number of embryos transferred with ectopic pregnancy after embryo transfer in patients with salpingectomy or proximal tubal occlusion |
| topic | interstitial pregnancy ectopic pregnancy ivf-et numbers of embryos transferred days of embryo transfer |
| url | https://www.imrpress.com/journal/CEOG/49/9/10.31083/j.ceog4909196 |
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