Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15–TGF‐β1 under aggravated afterload

Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15–TGF‐β1 under aggravated afterload

Abstract Pathological cardiac hypertrophy exhibits complex and abnormal gene expression patterns and progresses to heart failure. Forkhead box protein O6 (FoxO6) is a key transcription factor involved in many biological processes. This study aimed to explore the role of FoxO6 in cardiac hypertrophy....

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Bibliographic Details
Main Authors: Bing Zhang, Lei Shi, Yanzhen Tan, Yenong Zhou, Jun Cui, Yujie Song, Yingying Liu, Miao Zhang, Weixun Duan, Zhenxiao Jin, Jincheng Liu, Dinghua Yi, Yang Sun, Wei Yi
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:MedComm
Subjects:
cardiac fibrosis
FoxO6
heart failure
Kif15
TGF‐β1
Online Access:https://doi.org/10.1002/mco2.383

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