The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses
Studies assessing the clinical and radiographic success of LSTR in terms of the presence of pain, mobility, swelling, fistula/sinus tract, interradicular radiolucency, and root resorption have not been performed. We therefore performed a systematic review with the aim of evaluating the effectiveness...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-09-01
|
| Series: | Saudi Dental Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S101390522300113X |
| _version_ | 1797676320657768448 |
|---|---|
| author | Nabras Alrayes Yara Almaimouni Abrar Tounsi Khalid Tarabzouni Faisal Alonaizan Maria Salem Ibrahim |
| author_facet | Nabras Alrayes Yara Almaimouni Abrar Tounsi Khalid Tarabzouni Faisal Alonaizan Maria Salem Ibrahim |
| author_sort | Nabras Alrayes |
| collection | DOAJ |
| description | Studies assessing the clinical and radiographic success of LSTR in terms of the presence of pain, mobility, swelling, fistula/sinus tract, interradicular radiolucency, and root resorption have not been performed. We therefore performed a systematic review with the aim of evaluating the effectiveness of lesion sterilization and tissue repair (LSTR), using three antibacterial mixtures (3Mix), in treating primary teeth. Well-defined search strategies developed for four electronic databases, Web of Science, OVID, PubMed, and Scopus, were used in this study. Two independent reviewers selected relevant articles from 3,232 studies by screening titles and abstracts. Based on the inclusion criteria, 25 articles were selected. Eight analyses of clinical and radiographic results were conducted based on 6, 12, 18, and 24-month follow-up intervals. Data extraction and quality appraisal were performed by three independent reviewers. The composition of antibiotic mixtures used for LSTR varied substantially, with inconsistent radiographic and clinical success rates across the included studies. A quantitative grouping of the studies showed no significant differences between 3Mix and the control medicaments regarding radiographical and clinical success (p-value > 0.05). The available evidence on different LSTR using 3Mix is scarce, and the study findings were inconsistent. Therefore, additional clinical trials on 3Mix with different compositions are needed. |
| first_indexed | 2024-03-11T22:27:18Z |
| format | Article |
| id | doaj.art-da2ffb753926420282818bf9d3b5bf8f |
| institution | Directory Open Access Journal |
| issn | 1013-9052 |
| language | English |
| last_indexed | 2024-03-11T22:27:18Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj.art-da2ffb753926420282818bf9d3b5bf8f2023-09-24T05:14:20ZengElsevierSaudi Dental Journal1013-90522023-09-01356575588The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analysesNabras Alrayes0Yara Almaimouni1Abrar Tounsi2Khalid Tarabzouni3Faisal Alonaizan4Maria Salem Ibrahim5College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi ArabiaDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi ArabiaDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia; Corresponding author.Dhahran Armed Forces Hospital, Dhahran 31932, Saudi ArabiaDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi ArabiaDepartment of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi ArabiaStudies assessing the clinical and radiographic success of LSTR in terms of the presence of pain, mobility, swelling, fistula/sinus tract, interradicular radiolucency, and root resorption have not been performed. We therefore performed a systematic review with the aim of evaluating the effectiveness of lesion sterilization and tissue repair (LSTR), using three antibacterial mixtures (3Mix), in treating primary teeth. Well-defined search strategies developed for four electronic databases, Web of Science, OVID, PubMed, and Scopus, were used in this study. Two independent reviewers selected relevant articles from 3,232 studies by screening titles and abstracts. Based on the inclusion criteria, 25 articles were selected. Eight analyses of clinical and radiographic results were conducted based on 6, 12, 18, and 24-month follow-up intervals. Data extraction and quality appraisal were performed by three independent reviewers. The composition of antibiotic mixtures used for LSTR varied substantially, with inconsistent radiographic and clinical success rates across the included studies. A quantitative grouping of the studies showed no significant differences between 3Mix and the control medicaments regarding radiographical and clinical success (p-value > 0.05). The available evidence on different LSTR using 3Mix is scarce, and the study findings were inconsistent. Therefore, additional clinical trials on 3Mix with different compositions are needed.http://www.sciencedirect.com/science/article/pii/S101390522300113X3MixLesion SterilizationPrimary TeethAntibacterial MixturePulpectomyNon-instrumentation |
| spellingShingle | Nabras Alrayes Yara Almaimouni Abrar Tounsi Khalid Tarabzouni Faisal Alonaizan Maria Salem Ibrahim The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses Saudi Dental Journal 3Mix Lesion Sterilization Primary Teeth Antibacterial Mixture Pulpectomy Non-instrumentation |
| title | The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses |
| title_full | The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses |
| title_fullStr | The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses |
| title_full_unstemmed | The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses |
| title_short | The effect of an antibacterial mixture and non-instrumentation endodontic treatment in primary teeth: A systematic review and meta-analyses |
| title_sort | effect of an antibacterial mixture and non instrumentation endodontic treatment in primary teeth a systematic review and meta analyses |
| topic | 3Mix Lesion Sterilization Primary Teeth Antibacterial Mixture Pulpectomy Non-instrumentation |
| url | http://www.sciencedirect.com/science/article/pii/S101390522300113X |
| work_keys_str_mv | AT nabrasalrayes theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT yaraalmaimouni theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT abrartounsi theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT khalidtarabzouni theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT faisalalonaizan theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT mariasalemibrahim theeffectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT nabrasalrayes effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT yaraalmaimouni effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT abrartounsi effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT khalidtarabzouni effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT faisalalonaizan effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses AT mariasalemibrahim effectofanantibacterialmixtureandnoninstrumentationendodontictreatmentinprimaryteethasystematicreviewandmetaanalyses |