4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis
Root extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/12/14046 |
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| author | Antoniana U. Krettli Lucas S. Madureira Lucia M. X. Lopes Tito da Silva Marcos D. P. Pereira Julio Zukerman-Schpector |
| author_facet | Antoniana U. Krettli Lucas S. Madureira Lucia M. X. Lopes Tito da Silva Marcos D. P. Pereira Julio Zukerman-Schpector |
| author_sort | Antoniana U. Krettli |
| collection | DOAJ |
| description | Root extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6S,7E)-6,9-dihydroxy-10-(2'-hydroxy-ethoxy)-4,7-megastigmadien-3-one, 3], together with bulnesol and sitosterol-3-O-β-D-glucopyranoside. The structures of these compounds were determined by spectroscopic analyses and B3LYP/STO-3G** theoretical studies. |
| first_indexed | 2024-04-12T02:40:12Z |
| format | Article |
| id | doaj.art-da34557243d4454a8396ccbe941d9149 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T02:40:12Z |
| publishDate | 2012-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-da34557243d4454a8396ccbe941d91492022-12-22T03:51:20ZengMDPI AGMolecules1420-30492012-11-011712140461405710.3390/molecules1712140464,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformisAntoniana U. KrettliLucas S. MadureiraLucia M. X. LopesTito da SilvaMarcos D. P. PereiraJulio Zukerman-SchpectorRoot extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6S,7E)-6,9-dihydroxy-10-(2'-hydroxy-ethoxy)-4,7-megastigmadien-3-one, 3], together with bulnesol and sitosterol-3-O-β-D-glucopyranoside. The structures of these compounds were determined by spectroscopic analyses and B3LYP/STO-3G** theoretical studies.http://www.mdpi.com/1420-3049/17/12/14046Holostylis reniformisAristolochiaceaesesquiterpene4,5-seco-guaianemegastigmane |
| spellingShingle | Antoniana U. Krettli Lucas S. Madureira Lucia M. X. Lopes Tito da Silva Marcos D. P. Pereira Julio Zukerman-Schpector 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis Molecules Holostylis reniformis Aristolochiaceae sesquiterpene 4,5-seco-guaiane megastigmane |
| title | 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis |
| title_full | 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis |
| title_fullStr | 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis |
| title_full_unstemmed | 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis |
| title_short | 4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis |
| title_sort | 4 5 seco guaiane and a nine membered sesquiterpene lactone from holostylis reniformis |
| topic | Holostylis reniformis Aristolochiaceae sesquiterpene 4,5-seco-guaiane megastigmane |
| url | http://www.mdpi.com/1420-3049/17/12/14046 |
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