BoolSi: A Tool for Distributed Simulations and Analysis of Boolean Networks

We present BoolSi, an open-source cross-platform command line tool for distributed simulations of synchronous Boolean networks. It uses MPI standard to support execution on computational clusters, as well as parallel processing on a single computer. BoolSi can be used to model the behavior of comple...

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Bibliographic Details
Main Authors: Vladyslav Oles, Anton Kukushkin
Format: Article
Language:English
Published: Ubiquity Press 2020-10-01
Series:Journal of Open Research Software
Subjects:
Online Access:https://openresearchsoftware.metajnl.com/articles/308
Description
Summary:We present BoolSi, an open-source cross-platform command line tool for distributed simulations of synchronous Boolean networks. It uses MPI standard to support execution on computational clusters, as well as parallel processing on a single computer. BoolSi can be used to model the behavior of complex dynamic networks, such as gene regulatory networks. In particular, it allows for identification and statistical analysis of network attractors. We perform a case study of the activity of a cambium cell to demonstrate the capabilities of the tool.
ISSN:2049-9647