The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs
The objective of the present study was to study the comparative effect of administering selenium nanoparticles and sodium selenite in pregnant ewes on the blood serum levels of thyroxin in newly born lambs. For this purpose, twenty, four-month pregnant ewes within the same age were used. During the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
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Islamic Azad University, Tabriz Branch
2017-01-01
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| Series: | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
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| Online Access: | http://jvcp.iaut.ac.ir/article_527531_38f0175f20ce628f4a2bcc4307320227.pdf |
| _version_ | 1818362509623558144 |
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| author | Vahid Tabatabaei Gholamali Kojouri Afshin Jafari Abdonaser Mohebi |
| author_facet | Vahid Tabatabaei Gholamali Kojouri Afshin Jafari Abdonaser Mohebi |
| author_sort | Vahid Tabatabaei |
| collection | DOAJ |
| description | The objective of the present study was to study the comparative effect of administering selenium nanoparticles and sodium selenite in pregnant ewes on the blood serum levels of thyroxin in newly born lambs. For this purpose, twenty, four-month pregnant ewes within the same age were used. During the 21 days leading up to birth, supplementation of selenium nanoparticles (Se NPs) with dosages of 0.05 and 0.10 mg/kg B.W. were respectively fed to treatment groups 1 and 2. And supplementation with sodium selenite with dosage of 0.1 mg/kg B.W. was fed to treatment group 3. At the same time the control group was fed distilled water in equal volume. The ewes were monitored under accurate laboratory and clinical examination until the time of delivery. Neonatal lamb serum thyroxin level was measured at the day zero (birth day) and also at the 7th day. The results indicated that serum thyroxin level of neonatal lambs of treated groups 1 and 3, decreased significantly at 7 days' age in comparison to the birth day (p values less than 0.006 and 0.001, respectively). Results also showed that serum thyroxin level of group 2 offspring lambs on the day 0 was significantly less than that in group 1 (p=0.003). It was concluded that the physiological function of selenium nanoparticles was dose dependent, and the 0.05 mg/kg B.W. dosage of Se NPs induced similar effects like 0.1 mg/Kg B.W. of sodium selenite, which resulted in increasing serum level of thyroxin at the day of birth. Conflict of interest: None declared. |
| first_indexed | 2024-12-13T21:33:43Z |
| format | Article |
| id | doaj.art-da389c4b5213443281f5af0b6567112e |
| institution | Directory Open Access Journal |
| issn | 2322-4746 2476-6984 |
| language | fas |
| last_indexed | 2024-12-13T21:33:43Z |
| publishDate | 2017-01-01 |
| publisher | Islamic Azad University, Tabriz Branch |
| record_format | Article |
| series | Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī |
| spelling | doaj.art-da389c4b5213443281f5af0b6567112e2022-12-21T23:30:44ZfasIslamic Azad University, Tabriz BranchĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī2322-47462476-69842017-01-01104 (40) زمستان307314527531The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambsVahid Tabatabaei0Gholamali Kojouri1Afshin Jafari2Abdonaser Mohebi3Board certified in large animal internal medicineاستاد، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهرکرد، شهرکرد، ایران.استادیار، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهرکرد، شهرکرد، ایران.دانشیار، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهرکرد، شهرکرد، ایران.The objective of the present study was to study the comparative effect of administering selenium nanoparticles and sodium selenite in pregnant ewes on the blood serum levels of thyroxin in newly born lambs. For this purpose, twenty, four-month pregnant ewes within the same age were used. During the 21 days leading up to birth, supplementation of selenium nanoparticles (Se NPs) with dosages of 0.05 and 0.10 mg/kg B.W. were respectively fed to treatment groups 1 and 2. And supplementation with sodium selenite with dosage of 0.1 mg/kg B.W. was fed to treatment group 3. At the same time the control group was fed distilled water in equal volume. The ewes were monitored under accurate laboratory and clinical examination until the time of delivery. Neonatal lamb serum thyroxin level was measured at the day zero (birth day) and also at the 7th day. The results indicated that serum thyroxin level of neonatal lambs of treated groups 1 and 3, decreased significantly at 7 days' age in comparison to the birth day (p values less than 0.006 and 0.001, respectively). Results also showed that serum thyroxin level of group 2 offspring lambs on the day 0 was significantly less than that in group 1 (p=0.003). It was concluded that the physiological function of selenium nanoparticles was dose dependent, and the 0.05 mg/kg B.W. dosage of Se NPs induced similar effects like 0.1 mg/Kg B.W. of sodium selenite, which resulted in increasing serum level of thyroxin at the day of birth. Conflict of interest: None declared.http://jvcp.iaut.ac.ir/article_527531_38f0175f20ce628f4a2bcc4307320227.pdfSelenium nanoparticles (Se Nps)Sodium selenitelambThyroxinTransitional period |
| spellingShingle | Vahid Tabatabaei Gholamali Kojouri Afshin Jafari Abdonaser Mohebi The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī Selenium nanoparticles (Se Nps) Sodium selenite lamb Thyroxin Transitional period |
| title | The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| title_full | The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| title_fullStr | The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| title_full_unstemmed | The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| title_short | The comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| title_sort | comparative effect of selenium nanoparticles and sodium selenite supplementation in transitional period on serum thyroxin level of neonatal lambs |
| topic | Selenium nanoparticles (Se Nps) Sodium selenite lamb Thyroxin Transitional period |
| url | http://jvcp.iaut.ac.ir/article_527531_38f0175f20ce628f4a2bcc4307320227.pdf |
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