Decreased CD11c‐positive dendritic cells in the tumor microenvironment predict double‐hit/triple‐hit genotype and survival in diffuse large B‐cell lymphoma

Decreased CD11c‐positive dendritic cells in the tumor microenvironment predict double‐hit/triple‐hit genotype and survival in diffuse large B‐cell lymphoma

Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common type of non‐Hodgkin lymphoma and is a potentially curable disease. However, it is heterogenous, and the prognosis is poor if the tumor cells harbor fusions involving MYC and BCL2 or MYC and BCL6 (double‐hit [DH] lymphoma), or fusions...

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Bibliographic Details
Main Authors: Chang‐Tsu Yuan, Shih‐Sung Chuang, Pei‐Yuan Cheng, Koping Chang, Hsuan Wang, Jia‐Huei Tsai, Jau‐Yu Liau, Wen‐Chien Chou
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:The Journal of Pathology: Clinical Research
Subjects:
high‐grade B‐cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements
double‐hit lymphoma
triple‐hit lymphoma
diffuse large B‐cell lymphoma
tumor microenvironment
dendritic cell
Online Access:https://doi.org/10.1002/cjp2.283

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