Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves
Failure of Passive Transfer (FPT) is a critical concern in neonatal calves, marked by inadequate maternal immunoglobulin transmission due to the syndesmochorial placenta. This leads to heightened disease prevalence, significantly impacting calf health and imposing substantial economic burdens. The p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca
2024-04-01
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| Series: | Cluj Veterinary Journal |
| Subjects: | |
| Online Access: | https://clujveterinaryjournal.ro/index.php/cvj/article/view/62 |
| _version_ | 1797216330392272896 |
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| author | Florin Petrisor Posastiuc Dragoș Adrian Popescu Nicolae Tiberiu Constantin Florina Marian Crina Raluca Andrei Mario Darius Codreanu |
| author_facet | Florin Petrisor Posastiuc Dragoș Adrian Popescu Nicolae Tiberiu Constantin Florina Marian Crina Raluca Andrei Mario Darius Codreanu |
| author_sort | Florin Petrisor Posastiuc |
| collection | DOAJ |
| description | Failure of Passive Transfer (FPT) is a critical concern in neonatal calves, marked by inadequate maternal immunoglobulin transmission due to the syndesmochorial placenta. This leads to heightened disease prevalence, significantly impacting calf health and imposing substantial economic burdens. The prevalence of FPT varies globally, with studies reporting incidence rates ranging from 13% to 41%, one of the explanations for such high variability being the use of different methods and non-adapted thresholds. Efficient diagnostic methodologies are essential to address this challenge, with ongoing exploration of alternative approaches beyond the established gold standard of radial immunodiffusion (RID). This review critically evaluates the available direct methods for FPT assessment gathering the most recent data on both established methods such as enzyme-linked immunosorbent assay (ELISA) and innovative methodologies such as immunoturbidimetry, split trehalase IgG assay (STIGA), ionization techniques (IT), mass spectrometry (MS), proteomics, and infrared spectroscopy (IS) with attenuated infrared spectroscopy (ATR). Exploring beyond conventional practices is vital for enhancing diagnostic accuracy and addressing the complexities of FPT in calf health management.
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| first_indexed | 2024-04-24T11:44:15Z |
| format | Article |
| id | doaj.art-da3a98e3651248f9ba6ef42dbf43f69b |
| institution | Directory Open Access Journal |
| issn | 2066-9399 |
| language | English |
| last_indexed | 2024-04-24T11:44:15Z |
| publishDate | 2024-04-01 |
| publisher | University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca |
| record_format | Article |
| series | Cluj Veterinary Journal |
| spelling | doaj.art-da3a98e3651248f9ba6ef42dbf43f69b2024-04-09T12:03:50ZengUniversity of Agricultural Sciences and Veterinary Medicine Cluj-NapocaCluj Veterinary Journal2066-93992024-04-0129110.52331/nqpej009Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal CalvesFlorin Petrisor Posastiuc0Dragoș Adrian PopescuNicolae Tiberiu ConstantinFlorina MarianCrina Raluca AndreiMario Darius CodreanuFaculty of Veterinary Medicine of Bucharest, University of Agronomic Sciences and Veterinary Medicine, Bucharest, Romania; Faculty of Veterinary Medicine, Ghent University, Merelbeke, BelgiumFailure of Passive Transfer (FPT) is a critical concern in neonatal calves, marked by inadequate maternal immunoglobulin transmission due to the syndesmochorial placenta. This leads to heightened disease prevalence, significantly impacting calf health and imposing substantial economic burdens. The prevalence of FPT varies globally, with studies reporting incidence rates ranging from 13% to 41%, one of the explanations for such high variability being the use of different methods and non-adapted thresholds. Efficient diagnostic methodologies are essential to address this challenge, with ongoing exploration of alternative approaches beyond the established gold standard of radial immunodiffusion (RID). This review critically evaluates the available direct methods for FPT assessment gathering the most recent data on both established methods such as enzyme-linked immunosorbent assay (ELISA) and innovative methodologies such as immunoturbidimetry, split trehalase IgG assay (STIGA), ionization techniques (IT), mass spectrometry (MS), proteomics, and infrared spectroscopy (IS) with attenuated infrared spectroscopy (ATR). Exploring beyond conventional practices is vital for enhancing diagnostic accuracy and addressing the complexities of FPT in calf health management. https://clujveterinaryjournal.ro/index.php/cvj/article/view/62failure of passive transferradial immunodiffusioncalf managementimmunoglobulinstotal serum protein |
| spellingShingle | Florin Petrisor Posastiuc Dragoș Adrian Popescu Nicolae Tiberiu Constantin Florina Marian Crina Raluca Andrei Mario Darius Codreanu Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves Cluj Veterinary Journal failure of passive transfer radial immunodiffusion calf management immunoglobulins total serum protein |
| title | Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves |
| title_full | Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves |
| title_fullStr | Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves |
| title_full_unstemmed | Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves |
| title_short | Comprehensive Evaluation of Direct Methods for Failure of Passive Transfer Diagnosis in Neonatal Calves |
| title_sort | comprehensive evaluation of direct methods for failure of passive transfer diagnosis in neonatal calves |
| topic | failure of passive transfer radial immunodiffusion calf management immunoglobulins total serum protein |
| url | https://clujveterinaryjournal.ro/index.php/cvj/article/view/62 |
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