Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm
Background/Aim. Renal cell carcinoma (RCC) is the third most frequent urological carcinoma. Radical nephrectomy (RN) is considered as the gold standard in the treatment of localized RCC, but recently the use of minimally invasive techniques are more frequently used. The aim of this study is to deter...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2017-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600254M.pdf |
| _version_ | 1819089411209428992 |
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| author | Marić Predrag Jovanović Mirko Milović Novak Stamenković Dušica Košević Branko Aleksić Predrag Cerović Snežana Spasić Aleksandar Simić Dejan Rašković Jelena |
| author_facet | Marić Predrag Jovanović Mirko Milović Novak Stamenković Dušica Košević Branko Aleksić Predrag Cerović Snežana Spasić Aleksandar Simić Dejan Rašković Jelena |
| author_sort | Marić Predrag |
| collection | DOAJ |
| description | Background/Aim. Renal cell carcinoma (RCC) is the third most frequent urological carcinoma. Radical nephrectomy (RN) is considered as the gold standard in the treatment of localized RCC, but recently the use of minimally invasive techniques are more frequently used. The aim of this study is to determine is there a difference in the incidence of complications in the group of patients treated by RN and partial nephrectomy (PN) for renal cell carcinoma up to 7 cm. Methods. The retrospective study included the analysis of the medical history of patients surgically treated in the six years period. The inclusion criteria were RCC size up to 7 cm and no detectable metastasis. The exclusion criterion was the presence of a bilateral tumor. Intraoperative and early postoperative complications were followed-up. The Clavien- Dindo grade system was used for classification of surgical complications. Results. In six years period 481 (76.35%) radical transperitoneal nephrectomies and 149 (23.65%) partial nephrectomies were performed. Bilateral RCCs were verified in 2.06% (13/630), an initial metastatic disease in 15.8% (100/630) and lymph node involvement in 7.14% (45/630) of the patients and their data were not included in analysis. Therefore, data from 120 patients with RN and 97 patients with PN who fulfill inclusion criteria were analyzed. Complications were recorded in 29.5% (64/217) of patients. Significantly less patients had complications in the RN group [22.5 % (27/120)] compared to the PN group [38.1% (37/97)] (p = 0.006). These complications were mostly grade I and II. Complications grade III and IV were only present in the group of patients treated by PN. Conclusion. Based on our data in selected patients with renal cell carcinoma in stage T1, PN is a proper and safe choice. The patient must be involved in making the definitive decision of modalities of surgical treatment. |
| first_indexed | 2024-12-21T22:07:30Z |
| format | Article |
| id | doaj.art-da3f8a55f2264f71a3f03ab63838e04c |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-12-21T22:07:30Z |
| publishDate | 2017-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-da3f8a55f2264f71a3f03ab63838e04c2022-12-21T18:48:41ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202017-01-0174763964310.2298/VSP151017254M0042-84501600254MComplications of radical and partial nephrectomy for renal cell carcinoma up to 7 cmMarić Predrag0Jovanović Mirko1Milović Novak2Stamenković Dušica3Košević Branko4Aleksić Predrag5Cerović Snežana6Spasić Aleksandar7Simić Dejan8Rašković Jelena9Military Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic of Anesthesiology and Intensive Care, Belgrade Military Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute for Pathology and Forensic Medicine, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeSchool of Economics, Department of Statistics, BelgradeBackground/Aim. Renal cell carcinoma (RCC) is the third most frequent urological carcinoma. Radical nephrectomy (RN) is considered as the gold standard in the treatment of localized RCC, but recently the use of minimally invasive techniques are more frequently used. The aim of this study is to determine is there a difference in the incidence of complications in the group of patients treated by RN and partial nephrectomy (PN) for renal cell carcinoma up to 7 cm. Methods. The retrospective study included the analysis of the medical history of patients surgically treated in the six years period. The inclusion criteria were RCC size up to 7 cm and no detectable metastasis. The exclusion criterion was the presence of a bilateral tumor. Intraoperative and early postoperative complications were followed-up. The Clavien- Dindo grade system was used for classification of surgical complications. Results. In six years period 481 (76.35%) radical transperitoneal nephrectomies and 149 (23.65%) partial nephrectomies were performed. Bilateral RCCs were verified in 2.06% (13/630), an initial metastatic disease in 15.8% (100/630) and lymph node involvement in 7.14% (45/630) of the patients and their data were not included in analysis. Therefore, data from 120 patients with RN and 97 patients with PN who fulfill inclusion criteria were analyzed. Complications were recorded in 29.5% (64/217) of patients. Significantly less patients had complications in the RN group [22.5 % (27/120)] compared to the PN group [38.1% (37/97)] (p = 0.006). These complications were mostly grade I and II. Complications grade III and IV were only present in the group of patients treated by PN. Conclusion. Based on our data in selected patients with renal cell carcinoma in stage T1, PN is a proper and safe choice. The patient must be involved in making the definitive decision of modalities of surgical treatment.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600254M.pdfkidney neoplasmsurologic surgical proceduresintraoperative complicationspostoperative periodpostoperative complications |
| spellingShingle | Marić Predrag Jovanović Mirko Milović Novak Stamenković Dušica Košević Branko Aleksić Predrag Cerović Snežana Spasić Aleksandar Simić Dejan Rašković Jelena Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm Vojnosanitetski Pregled kidney neoplasms urologic surgical procedures intraoperative complications postoperative period postoperative complications |
| title | Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| title_full | Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| title_fullStr | Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| title_full_unstemmed | Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| title_short | Complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| title_sort | complications of radical and partial nephrectomy for renal cell carcinoma up to 7 cm |
| topic | kidney neoplasms urologic surgical procedures intraoperative complications postoperative period postoperative complications |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600254M.pdf |
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