Lesão isquémica do SNC em doentes com lupus eritematoso sistémico.
In a review of 240 patients with Systemic Lupus Erythematosus we found 12 (5%) with cerebral infarctions. The average patient age was 38 years and no relation with the duration of lupus was found. The most common neurologic manifestations were hemiparesis (67%), language disturbances (25%) and ataxi...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ordem dos Médicos
1994-04-01
|
| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2892 |
| _version_ | 1811242241067319296 |
|---|---|
| author | M J Santos P Reis J A da Silva M V de Queiroz |
| author_facet | M J Santos P Reis J A da Silva M V de Queiroz |
| author_sort | M J Santos |
| collection | DOAJ |
| description | In a review of 240 patients with Systemic Lupus Erythematosus we found 12 (5%) with cerebral infarctions. The average patient age was 38 years and no relation with the duration of lupus was found. The most common neurologic manifestations were hemiparesis (67%), language disturbances (25%) and ataxia (25%). Clinical signs of diffuse involvement of Central Nervous System (CNS) were also present in 1/3 of the patients. In 5 cases (42%) no signs of lupus activity were found. In the remaining 7 (58%), where other manifestations occurred, all presented cutaneous vasculitis. Known risk factors for atherosclerotic vascular disease were common and 58% of the patients had at least one risk factor. In conclusion: 1. Recent onset cutaneous vasculitis should alert the physician to the possibility of CNS ischemic lesion and 2. The presence of risk factors for cerebrovascular disease (steroid therapy, hypertension and hypercholesterolemia) is frequent and may be controlled. |
| first_indexed | 2024-04-12T13:48:49Z |
| format | Article |
| id | doaj.art-da40bd6ba79e4b9e84b8e5d98bdd9185 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T13:48:49Z |
| publishDate | 1994-04-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-da40bd6ba79e4b9e84b8e5d98bdd91852022-12-22T03:30:35ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07581994-04-017410.20344/amp.2892Lesão isquémica do SNC em doentes com lupus eritematoso sistémico.M J Santos0P ReisJ A da SilvaM V de QueirozUnidade de Reumatologia do Hospital de Santa Maria, Lisboa.In a review of 240 patients with Systemic Lupus Erythematosus we found 12 (5%) with cerebral infarctions. The average patient age was 38 years and no relation with the duration of lupus was found. The most common neurologic manifestations were hemiparesis (67%), language disturbances (25%) and ataxia (25%). Clinical signs of diffuse involvement of Central Nervous System (CNS) were also present in 1/3 of the patients. In 5 cases (42%) no signs of lupus activity were found. In the remaining 7 (58%), where other manifestations occurred, all presented cutaneous vasculitis. Known risk factors for atherosclerotic vascular disease were common and 58% of the patients had at least one risk factor. In conclusion: 1. Recent onset cutaneous vasculitis should alert the physician to the possibility of CNS ischemic lesion and 2. The presence of risk factors for cerebrovascular disease (steroid therapy, hypertension and hypercholesterolemia) is frequent and may be controlled.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2892 |
| spellingShingle | M J Santos P Reis J A da Silva M V de Queiroz Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. Acta Médica Portuguesa |
| title | Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. |
| title_full | Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. |
| title_fullStr | Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. |
| title_full_unstemmed | Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. |
| title_short | Lesão isquémica do SNC em doentes com lupus eritematoso sistémico. |
| title_sort | lesao isquemica do snc em doentes com lupus eritematoso sistemico |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2892 |
| work_keys_str_mv | AT mjsantos lesaoisquemicadosncemdoentescomlupuseritematososistemico AT preis lesaoisquemicadosncemdoentescomlupuseritematososistemico AT jadasilva lesaoisquemicadosncemdoentescomlupuseritematososistemico AT mvdequeiroz lesaoisquemicadosncemdoentescomlupuseritematososistemico |