Abacavir: it’s use and hypersensitivity
Abacavir, a nucleoside reverse transcriptase inhibitor, is useful in first and second line therapy as well as a substitute for Stavudine and Zidovudine for toxicity. Although safe and well tolerated, a life threatening hypersensitivity reaction can occur. The risk for developing this reaction relate...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2009-12-01
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| Series: | Southern African Journal of HIV Medicine |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/265 |
| _version_ | 1818008464230711296 |
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| author | Helena Rabie Kristin Lorenc Henning Pierre Schoeman Nico de Villiers G HJ Pretorius Mark F Cotton |
| author_facet | Helena Rabie Kristin Lorenc Henning Pierre Schoeman Nico de Villiers G HJ Pretorius Mark F Cotton |
| author_sort | Helena Rabie |
| collection | DOAJ |
| description | Abacavir, a nucleoside reverse transcriptase inhibitor, is useful in first and second line therapy as well as a substitute for Stavudine and Zidovudine for toxicity. Although safe and well tolerated, a life threatening hypersensitivity reaction can occur. The risk for developing this reaction relates to the presence of specific genotypes especially HLA-B*5701. |
| first_indexed | 2024-04-14T05:29:35Z |
| format | Article |
| id | doaj.art-da40c1b438114c89aabda76a24bb47ae |
| institution | Directory Open Access Journal |
| issn | 1608-9693 2078-6751 |
| language | English |
| last_indexed | 2024-04-14T05:29:35Z |
| publishDate | 2009-12-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of HIV Medicine |
| spelling | doaj.art-da40c1b438114c89aabda76a24bb47ae2022-12-22T02:09:51ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512009-12-0110410.4102/sajhivmed.v10i4.265265Abacavir: it’s use and hypersensitivityHelena RabieKristin Lorenc HenningPierre SchoemanNico de VilliersG HJ PretoriusMark F CottonAbacavir, a nucleoside reverse transcriptase inhibitor, is useful in first and second line therapy as well as a substitute for Stavudine and Zidovudine for toxicity. Although safe and well tolerated, a life threatening hypersensitivity reaction can occur. The risk for developing this reaction relates to the presence of specific genotypes especially HLA-B*5701.https://sajhivmed.org.za/index.php/hivmed/article/view/265 |
| spellingShingle | Helena Rabie Kristin Lorenc Henning Pierre Schoeman Nico de Villiers G HJ Pretorius Mark F Cotton Abacavir: it’s use and hypersensitivity Southern African Journal of HIV Medicine |
| title | Abacavir: it’s use and hypersensitivity |
| title_full | Abacavir: it’s use and hypersensitivity |
| title_fullStr | Abacavir: it’s use and hypersensitivity |
| title_full_unstemmed | Abacavir: it’s use and hypersensitivity |
| title_short | Abacavir: it’s use and hypersensitivity |
| title_sort | abacavir it s use and hypersensitivity |
| url | https://sajhivmed.org.za/index.php/hivmed/article/view/265 |
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