25-Hydroxylation of vitamin D3 in the human hepatoma cell lines Hep G2 and Hep 3B.

Two human hepatoma cell lines, Hep G2 and Hep 3B, were screened for vitamin D3-25-hydroxylase enzyme activity by incubation with radioactive vitamin D3. A compound co-chromatographing with 25-OH-D3 was synthesized in both cell lines but its rate of synthesis was tenfold greater in Hep 3B than in Hep...

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Bibliographic Details
Main Authors: S P Tam, S Strugnell, R G Deeley, G Jones
Format: Article
Language:English
Published: Elsevier 1988-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520384054