Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis
Abstract Background Viridans group streptococci of the Streptococcus mitis-oralis subgroup are important endovascular pathogens. They can rapidly develop high-level and durable non-susceptibility to daptomycin both in vitro and in vivo upon exposure to daptomycin. Two consistent genetic adaptations...
Main Authors: | Allison Parrett, Joseph M. Reed, Stewart G. Gardner, Nagendra N. Mishra, Arnold S. Bayer, Robert Powers, Greg A. Somerville |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
|
Series: | BMC Microbiology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12866-020-01849-w |
Similar Items
-
Strain-Specific Adaptations of <i>Streptococcus mitis-oralis</i> to Serial In Vitro Passage in Daptomycin (DAP): Genotypic and Phenotypic Characteristics
by: Nagendra N. Mishra, et al.
Published: (2020-08-01) -
Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in <i>Streptococcus mitis-oralis</i>
by: Michael R. Yeaman, et al.
Published: (2021-04-01) -
Activity of the Lactate Dehydrogenase Inhibitor Oxamic Acid against the Fermentative Bacterium <i>Streptococcus mitis/oralis</i>: Bactericidal Effects and Prevention of Daptomycin Resistance In Vitro and in an Ex Vivo Model
by: Razieh Kebriaei, et al.
Published: (2022-10-01) -
Membrane Phenotypic, Metabolic and Genotypic Adaptations of <i>Streptococcus oralis</i> Strains Destined to Rapidly Develop Stable, High-Level Daptomycin Resistance during Daptomycin Exposures
by: Nagendra N. Mishra, et al.
Published: (2023-06-01) -
The interplay between daptomycin and the immune system
by: Theodoros eKelesidis
Published: (2014-02-01)