The interacting physiology of COVID‐19 and the renin‐angiotensin‐aldosterone system: Key agents for treatment

The interacting physiology of COVID‐19 and the renin‐angiotensin‐aldosterone system: Key agents for treatment

Abstract SARS‐CoV‐2 interacting with its receptor, angiotensin‐converting enzyme 2 (ACE2), turns the host response to viral infection into a dysregulated uncontrolled inflammatory response. This is because ACE2 limits the production of the peptide angiotensin II (Ang II) and SARS‐CoV‐2, through the...

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Bibliographic Details
Main Authors: Eugenie R. Lumbers, Richard Head, Gary R. Smith, Sarah J. Delforce, Bevyn Jarrott, Jennifer H.Martin, Kirsty G. Pringle
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Pharmacology Research & Perspectives
Subjects:
ACE2
COVID‐19
inflammation
renin‐angiotensin‐aldosterone system
therapies
Online Access:https://doi.org/10.1002/prp2.917

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