USP35 promotes HCC development by stabilizing ABHD17C and activating the PI3K/AKT signaling pathway
Abstract S-palmitoylation is a reversible protein lipidation that controls the subcellular localization and function of targeted proteins, including oncogenes such as N-RAS. The depalmitoylation enzyme family ABHD17s can remove the S-palmitoylation from N-RAS to facilitate cancer development. We pre...
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Nature Publishing Group
2023-11-01
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| Σειρά: | Cell Death Discovery |
| Διαθέσιμο Online: | https://doi.org/10.1038/s41420-023-01714-5 |