Biochemical Neuroadaptations in the Rat Striatal Dopaminergic System after Prolonged Exposure to Methamphetamine Self-Administration

Biochemical Neuroadaptations in the Rat Striatal Dopaminergic System after Prolonged Exposure to Methamphetamine Self-Administration

Perturbations in striatal dopamine (DA) homeostasis might underlie the behavioral and pathobiological consequences of METH use disorder in humans. To identify potential consequences of long-term METH exposure, we modeled the adverse consequence DSM criterion of substance use disorders by giving foot...

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Bibliographic Details
Main Authors: Subramaniam Jayanthi, Bruce Ladenheim, Patricia Sullivan, Michael T. McCoy, Irina N. Krasnova, David S. Goldstein, Jean Lud Cadet
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine
dopamine metabolites
DOPAL
dopamine receptors
dorsal striatum
methamphetamine use disorder
Online Access:https://www.mdpi.com/1422-0067/23/17/10092

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