In-Depth Immunological Typization of Children with Sickle Cell Disease: A Preliminary Insight into Its Plausible Correlation with Clinical Course and Hydroxyurea Therapy

In-Depth Immunological Typization of Children with Sickle Cell Disease: A Preliminary Insight into Its Plausible Correlation with Clinical Course and Hydroxyurea Therapy

Sickle cell disease (SCD) is a condition of functional hypo-/a-splenism in which predisposition to bacterial infections is only a facet of a wide spectrum of immune-dysregulation disorders forming the clinical expression of a peculiar immunophenotype. The objective of this study was to perform an in...

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Bibliographic Details
Main Authors: Giulia Giulietti, Daniele Zama, Francesca Conti, Mattia Moratti, Maria Teresa Presutti, Tamara Belotti, Maria Elena Cantarini, Elena Facchini, Mirna Bassi, Paola Selva, Elisabetta Magrini, Marcello Lanari, Andrea Pession
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
children
clinical course
hydroxyurea
immunological typization
immunophenotyping
pediatric
Online Access:https://www.mdpi.com/2077-0383/11/11/3037

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