Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro

Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro

To achieve the goal of a first-in-human trial for human induced pluripotent stem cell (hiPSC)-based transplantation for the treatment of various diseases, allogeneic human leukocyte antigen (HLA)-matched hiPSC cell banks represent a realistic tool from the perspective of quality control and cost per...

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Bibliographic Details
Main Authors: Masahiro Ozaki, Akio Iwanami, Narihito Nagoshi, Jun Kohyama, Go Itakura, Hiroki Iwai, Soraya Nishimura, Yuichiro Nishiyama, Soya Kawabata, Keiko Sugai, Tsuyoshi Iida, Kohei Matsubayashi, Miho Isoda, Rei Kashiwagi, Yoshiaki Toyama, Morio Matsumoto, Hideyuki Okano, Masaya Nakamura
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Stem Cell Research
Subjects:
iPS cell-derived neural stem/progenitor cells
HLA
Mixed lymphocyte reaction
Immunomodulatory function
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300077

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