Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma
Renal clear cell carcinoma (ccRCC) and the tumor microenvironment (TME) influence each other, leading to the tumor microenvironment that can guide the corresponding treatment. With the deepening of research, some treatment options have achieved good results, such as tyrosine kinase inhibitors, immun...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-01-01
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| Series: | Cancer Control |
| Online Access: | https://doi.org/10.1177/10732748231155700 |
| _version_ | 1797838873091375104 |
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| author | Yongqiang Huang MD Hong Sun MD Pu Guo MD |
| author_facet | Yongqiang Huang MD Hong Sun MD Pu Guo MD |
| author_sort | Yongqiang Huang MD |
| collection | DOAJ |
| description | Renal clear cell carcinoma (ccRCC) and the tumor microenvironment (TME) influence each other, leading to the tumor microenvironment that can guide the corresponding treatment. With the deepening of research, some treatment options have achieved good results, such as tyrosine kinase inhibitors, immune checkpoint inhibitors, and so on. As the link between TME and malignancy is constantly discovered, more targeted studies on different components of TME are increasing, and this targeted therapy is a new method for treating ccRCC, and also a current research hotspot. This review summarizes the characteristics of the ccRCC tumor microenvironment, the outcomes of different treatments, and some potential targets. |
| first_indexed | 2024-04-09T15:48:59Z |
| format | Article |
| id | doaj.art-da5beda074e7413a9d2fc966ef73abae |
| institution | Directory Open Access Journal |
| issn | 1526-2359 |
| language | English |
| last_indexed | 2024-04-09T15:48:59Z |
| publishDate | 2023-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cancer Control |
| spelling | doaj.art-da5beda074e7413a9d2fc966ef73abae2023-04-26T16:04:06ZengSAGE PublishingCancer Control1526-23592023-01-013010.1177/10732748231155700Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell CarcinomaYongqiang Huang MDHong Sun MDPu Guo MDRenal clear cell carcinoma (ccRCC) and the tumor microenvironment (TME) influence each other, leading to the tumor microenvironment that can guide the corresponding treatment. With the deepening of research, some treatment options have achieved good results, such as tyrosine kinase inhibitors, immune checkpoint inhibitors, and so on. As the link between TME and malignancy is constantly discovered, more targeted studies on different components of TME are increasing, and this targeted therapy is a new method for treating ccRCC, and also a current research hotspot. This review summarizes the characteristics of the ccRCC tumor microenvironment, the outcomes of different treatments, and some potential targets.https://doi.org/10.1177/10732748231155700 |
| spellingShingle | Yongqiang Huang MD Hong Sun MD Pu Guo MD Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma Cancer Control |
| title | Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma |
| title_full | Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma |
| title_fullStr | Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma |
| title_full_unstemmed | Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma |
| title_short | Research Progress of Tumor Microenvironment Targeted Therapy for Clear Cell Renal Cell Carcinoma |
| title_sort | research progress of tumor microenvironment targeted therapy for clear cell renal cell carcinoma |
| url | https://doi.org/10.1177/10732748231155700 |
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