Genetically engineered mouse models of pituitary tumors

Genetically engineered mouse models of pituitary tumors

Animal models constitute valuable tools for investigating the pathogenesis of cancer as well as for preclinical testing of novel therapeutics approaches. However, the pathogenic mechanisms of pituitary tumor formation remain poorly understood, particularly in sporadic adenomas, thus making it a chal...

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Bibliographic Details
Main Authors: David A Cano, Alfonso eSoto-Moreno, Alfonso eLeal-Cerro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Oncology
Subjects:
Adenoma
mouse models
Transgenic mice
Pituitary
GEMMs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00203/full

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