PCR-like performance of rapid test with permselective tunable nanotrap
Lateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold.
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37018-6 |
| _version_ | 1797864248042323968 |
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| author | Seong Jun Park Seungmin Lee Dongtak Lee Na Eun Lee Jeong Soo Park Ji Hye Hong Jae Won Jang Hyunji Kim Seokbeom Roh Gyudo Lee Dongho Lee Sung-Yeon Cho Chulmin Park Dong-Gun Lee Raeseok Lee Dukhee Nho Dae Sung Yoon Yong Kyoung Yoo Jeong Hoon Lee |
| author_facet | Seong Jun Park Seungmin Lee Dongtak Lee Na Eun Lee Jeong Soo Park Ji Hye Hong Jae Won Jang Hyunji Kim Seokbeom Roh Gyudo Lee Dongho Lee Sung-Yeon Cho Chulmin Park Dong-Gun Lee Raeseok Lee Dukhee Nho Dae Sung Yoon Yong Kyoung Yoo Jeong Hoon Lee |
| author_sort | Seong Jun Park |
| collection | DOAJ |
| description | Lateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold. |
| first_indexed | 2024-04-09T22:48:42Z |
| format | Article |
| id | doaj.art-da63d1a44b61457f98e17256c82ad9aa |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T22:48:42Z |
| publishDate | 2023-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-da63d1a44b61457f98e17256c82ad9aa2023-03-22T11:43:11ZengNature PortfolioNature Communications2041-17232023-03-0114111010.1038/s41467-023-37018-6PCR-like performance of rapid test with permselective tunable nanotrapSeong Jun Park0Seungmin Lee1Dongtak Lee2Na Eun Lee3Jeong Soo Park4Ji Hye Hong5Jae Won Jang6Hyunji Kim7Seokbeom Roh8Gyudo Lee9Dongho Lee10Sung-Yeon Cho11Chulmin Park12Dong-Gun Lee13Raeseok Lee14Dukhee Nho15Dae Sung Yoon16Yong Kyoung Yoo17Jeong Hoon Lee18Department of Electrical Engineering, Kwangwoon UniversityDepartment of Electrical Engineering, Kwangwoon UniversitySchool of Biomedical Engineering, Korea UniversityDepartment of Electrical Engineering, Kwangwoon UniversityDepartment of Electrical Engineering, Kwangwoon UniversityDepartment of Electrical Engineering, Kwangwoon UniversitySchool of Biomedical Engineering, Korea UniversitySchool of Biomedical Engineering, Korea UniversityDepartment of Biotechnology and Bioinformatics, Korea UniversityDepartment of Biotechnology and Bioinformatics, Korea UniversityCALTH Inc.Vaccine Bio Research Institute, College of Medicine, The Catholic University of KoreaVaccine Bio Research Institute, College of Medicine, The Catholic University of KoreaVaccine Bio Research Institute, College of Medicine, The Catholic University of KoreaVaccine Bio Research Institute, College of Medicine, The Catholic University of KoreaVaccine Bio Research Institute, College of Medicine, The Catholic University of KoreaSchool of Biomedical Engineering, Korea UniversityDepartment of Electronic Engineering, Catholic Kwandong UniversityDepartment of Electrical Engineering, Kwangwoon UniversityLateral flow assays are valuable rapid diagnostic tests, but low sensitivity can hinder their precision. Here, the authors report an enrichment method using nanoporous AAO and red blood cell membranes, which when applied to patient samples prior to analysis can improve sensitivity up to 20-fold.https://doi.org/10.1038/s41467-023-37018-6 |
| spellingShingle | Seong Jun Park Seungmin Lee Dongtak Lee Na Eun Lee Jeong Soo Park Ji Hye Hong Jae Won Jang Hyunji Kim Seokbeom Roh Gyudo Lee Dongho Lee Sung-Yeon Cho Chulmin Park Dong-Gun Lee Raeseok Lee Dukhee Nho Dae Sung Yoon Yong Kyoung Yoo Jeong Hoon Lee PCR-like performance of rapid test with permselective tunable nanotrap Nature Communications |
| title | PCR-like performance of rapid test with permselective tunable nanotrap |
| title_full | PCR-like performance of rapid test with permselective tunable nanotrap |
| title_fullStr | PCR-like performance of rapid test with permselective tunable nanotrap |
| title_full_unstemmed | PCR-like performance of rapid test with permselective tunable nanotrap |
| title_short | PCR-like performance of rapid test with permselective tunable nanotrap |
| title_sort | pcr like performance of rapid test with permselective tunable nanotrap |
| url | https://doi.org/10.1038/s41467-023-37018-6 |
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