Perforated duodenal ulcer in a dog with gallbladder agenesis
Background: Duodenal ulceration (DU) in dogs derives from different causes but has never previously been related to gallbladder agenesis (GA). GA is a rare congenital disorder in dogs and is considered a predisposing factor for DU in humans. Case description: A 5-month-old intact female Maltese wa...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tripoli University
2023-06-01
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| Series: | Open Veterinary Journal |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=70062 |
| _version_ | 1797854961632018432 |
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| author | Luca Ciammaichella Armando Foglia Sara Del Magno Veronica Cola Stefano Zanardi Francesca Del Baldo Marco Pietra Maria Morini Luciano Pisoni |
| author_facet | Luca Ciammaichella Armando Foglia Sara Del Magno Veronica Cola Stefano Zanardi Francesca Del Baldo Marco Pietra Maria Morini Luciano Pisoni |
| author_sort | Luca Ciammaichella |
| collection | DOAJ |
| description | Background:
Duodenal ulceration (DU) in dogs derives from different causes but has never previously been related to gallbladder agenesis (GA). GA is a rare congenital disorder in dogs and is considered a predisposing factor for DU in humans.
Case description:
A 5-month-old intact female Maltese was presented for acute vomiting and diarrhea. Abdominal ultrasound suggested duodenal perforation and absence of the gallbladder. Exploratory laparotomy was performed to treat the perforation and confirmed GA. Hepatic ductal plate malformation (DPM) was histologically diagnosed in liver biopsy, but no signs of liver dysfunction were detected by blood work at first admission. Two months later, the dog developed signs of portal hypertension and medical treatment was started. However, the clinical condition gradually worsened until liver failure and the dog was euthanized 8 months after surgery. Necropsy confirmed hepatic abnormalities.
Conclusion:
This report describes a case of DU associated with GA and DPM in a dog. As in humans, GA may represent a hepatobiliary disease predisposing to gastroduodenal ulcerations. [Open Vet J 2023; 13(3.000): 376-381] |
| first_indexed | 2024-04-09T20:15:51Z |
| format | Article |
| id | doaj.art-da64d9275a944e6fb55e40699a2c222a |
| institution | Directory Open Access Journal |
| issn | 2226-4485 |
| language | English |
| last_indexed | 2024-04-09T20:15:51Z |
| publishDate | 2023-06-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj.art-da64d9275a944e6fb55e40699a2c222a2023-03-31T10:18:09ZengTripoli UniversityOpen Veterinary Journal2226-44852023-06-0113337638110.5455/OVJ.2023.v13.i3.1570062Perforated duodenal ulcer in a dog with gallbladder agenesisLuca Ciammaichella0Armando Foglia1Sara Del Magno2Veronica Cola3Stefano Zanardi4Francesca Del Baldo5Marco Pietra6Maria Morini7Luciano Pisoni8DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO) DIMEVET - Via Tolara di Sopra, 50 - Ozzano dell'Emilia (BO)Background: Duodenal ulceration (DU) in dogs derives from different causes but has never previously been related to gallbladder agenesis (GA). GA is a rare congenital disorder in dogs and is considered a predisposing factor for DU in humans. Case description: A 5-month-old intact female Maltese was presented for acute vomiting and diarrhea. Abdominal ultrasound suggested duodenal perforation and absence of the gallbladder. Exploratory laparotomy was performed to treat the perforation and confirmed GA. Hepatic ductal plate malformation (DPM) was histologically diagnosed in liver biopsy, but no signs of liver dysfunction were detected by blood work at first admission. Two months later, the dog developed signs of portal hypertension and medical treatment was started. However, the clinical condition gradually worsened until liver failure and the dog was euthanized 8 months after surgery. Necropsy confirmed hepatic abnormalities. Conclusion: This report describes a case of DU associated with GA and DPM in a dog. As in humans, GA may represent a hepatobiliary disease predisposing to gastroduodenal ulcerations. [Open Vet J 2023; 13(3.000): 376-381]http://www.ejmanager.com/fulltextpdf.php?mno=70062agenesisdogduodenumgallbladderulceration |
| spellingShingle | Luca Ciammaichella Armando Foglia Sara Del Magno Veronica Cola Stefano Zanardi Francesca Del Baldo Marco Pietra Maria Morini Luciano Pisoni Perforated duodenal ulcer in a dog with gallbladder agenesis Open Veterinary Journal agenesis dog duodenum gallbladder ulceration |
| title | Perforated duodenal ulcer in a dog with gallbladder agenesis |
| title_full | Perforated duodenal ulcer in a dog with gallbladder agenesis |
| title_fullStr | Perforated duodenal ulcer in a dog with gallbladder agenesis |
| title_full_unstemmed | Perforated duodenal ulcer in a dog with gallbladder agenesis |
| title_short | Perforated duodenal ulcer in a dog with gallbladder agenesis |
| title_sort | perforated duodenal ulcer in a dog with gallbladder agenesis |
| topic | agenesis dog duodenum gallbladder ulceration |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=70062 |
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