Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model

Ultrasound-Targeted Microbubble Destruction Alleviates Immunosuppression Induced by CD71+ Erythroid Progenitor Cells and Promotes PDL-1 Blockade Immunotherapy in the Lewis Lung Cancer Model

The CD71+ erythroid progenitor cells (CECs) exhibit distinctive immunosuppressive properties and regulate antitumor immunity to enable tumor growth. We presented a novel and non-invasive approach to improving immunity by targeting the splenic CECs via sonoporation generated by ultrasound-targeted mi...

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Bibliographic Details
Main Authors:	Xi Tan, Cuo Yi, Yi Zhang, Najiao Tang, Yali Xu, Zheng Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Oncology
Subjects:	CD71+ erythroid progenitor cells erythroid progenitor cells ultrasound-targeted microbubble destruction systematic immunity sonoporation
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.768222/full

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