Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years
Abstract Vibrio cholerae is responsible for the cause of severe life-threatening infection known as cholera. The study aimed to analyze the genetic make-up of V. cholerae O139 isolates from India and compare its phylogeny with the global strains. The genome data revealed that all isolates were of sa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-11-01
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| Series: | Gut Pathogens |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13099-017-0210-0 |
| _version_ | 1819226046898110464 |
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| author | Shalini Anandan Naveen Kumar Devanga Ragupathi Dhiviya Prabaa Muthuirulandi Sethuvel Suji Thangamani Balaji Veeraraghavan |
| author_facet | Shalini Anandan Naveen Kumar Devanga Ragupathi Dhiviya Prabaa Muthuirulandi Sethuvel Suji Thangamani Balaji Veeraraghavan |
| author_sort | Shalini Anandan |
| collection | DOAJ |
| description | Abstract Vibrio cholerae is responsible for the cause of severe life-threatening infection known as cholera. The study aimed to analyze the genetic make-up of V. cholerae O139 isolates from India and compare its phylogeny with the global strains. The genome data revealed that all isolates were of same sequence type (ST69) which belongs to seventh pandemic clone, with same virulence gene profile and, antimicrobial resistance gene profile except for two isolates. No known CRISPR repeats were identified in any of these isolates. Three different phages were identified among the isolates. All the isolates were found to harbour int SXT and seventh pandemic-specific gene (VC2346). Results from this study enhance our understanding on the persistence of ST69 V. cholerae O139 over 20 years. |
| first_indexed | 2024-12-23T10:19:16Z |
| format | Article |
| id | doaj.art-da6ab32548174c5b9028c27c331a916c |
| institution | Directory Open Access Journal |
| issn | 1757-4749 |
| language | English |
| last_indexed | 2024-12-23T10:19:16Z |
| publishDate | 2017-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Gut Pathogens |
| spelling | doaj.art-da6ab32548174c5b9028c27c331a916c2022-12-21T17:50:44ZengBMCGut Pathogens1757-47492017-11-01911710.1186/s13099-017-0210-0Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 yearsShalini Anandan0Naveen Kumar Devanga Ragupathi1Dhiviya Prabaa Muthuirulandi Sethuvel2Suji Thangamani3Balaji Veeraraghavan4Department of Clinical Microbiology, Christian Medical CollegeDepartment of Clinical Microbiology, Christian Medical CollegeDepartment of Clinical Microbiology, Christian Medical CollegeDepartment of Clinical Microbiology, Christian Medical CollegeDepartment of Clinical Microbiology, Christian Medical CollegeAbstract Vibrio cholerae is responsible for the cause of severe life-threatening infection known as cholera. The study aimed to analyze the genetic make-up of V. cholerae O139 isolates from India and compare its phylogeny with the global strains. The genome data revealed that all isolates were of same sequence type (ST69) which belongs to seventh pandemic clone, with same virulence gene profile and, antimicrobial resistance gene profile except for two isolates. No known CRISPR repeats were identified in any of these isolates. Three different phages were identified among the isolates. All the isolates were found to harbour int SXT and seventh pandemic-specific gene (VC2346). Results from this study enhance our understanding on the persistence of ST69 V. cholerae O139 over 20 years.http://link.springer.com/article/10.1186/s13099-017-0210-0Vibrio cholerae O139ST69MLSTAntimicrobial resistance |
| spellingShingle | Shalini Anandan Naveen Kumar Devanga Ragupathi Dhiviya Prabaa Muthuirulandi Sethuvel Suji Thangamani Balaji Veeraraghavan Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years Gut Pathogens Vibrio cholerae O139 ST69 MLST Antimicrobial resistance |
| title | Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years |
| title_full | Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years |
| title_fullStr | Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years |
| title_full_unstemmed | Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years |
| title_short | Prevailing clone (ST69) of Vibrio cholerae O139 in India over 10 years |
| title_sort | prevailing clone st69 of vibrio cholerae o139 in india over 10 years |
| topic | Vibrio cholerae O139 ST69 MLST Antimicrobial resistance |
| url | http://link.springer.com/article/10.1186/s13099-017-0210-0 |
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