Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing
Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37596-5 |
| _version_ | 1797849999184232448 |
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| author | Zhen-Dong Zhong Ying-Yuan Xie Hong-Xuan Chen Ye-Lin Lan Xue-Hong Liu Jing-Yun Ji Fu Wu Lingmei Jin Jiekai Chen Daniel W. Mak Zhang Zhang Guan-Zheng Luo |
| author_facet | Zhen-Dong Zhong Ying-Yuan Xie Hong-Xuan Chen Ye-Lin Lan Xue-Hong Liu Jing-Yun Ji Fu Wu Lingmei Jin Jiekai Chen Daniel W. Mak Zhang Zhang Guan-Zheng Luo |
| author_sort | Zhen-Dong Zhong |
| collection | DOAJ |
| description | Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing. |
| first_indexed | 2024-04-09T18:53:15Z |
| format | Article |
| id | doaj.art-da7983b5010a43419a87347461c7e37b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T18:53:15Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-da7983b5010a43419a87347461c7e37b2023-04-09T11:20:28ZengNature PortfolioNature Communications2041-17232023-04-0114111410.1038/s41467-023-37596-5Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencingZhen-Dong Zhong0Ying-Yuan Xie1Hong-Xuan Chen2Ye-Lin Lan3Xue-Hong Liu4Jing-Yun Ji5Fu Wu6Lingmei Jin7Jiekai Chen8Daniel W. Mak9Zhang Zhang10Guan-Zheng Luo11MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityCAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of SciencesCAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of SciencesSchool of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong KongMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityMOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen UniversityDirect RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.https://doi.org/10.1038/s41467-023-37596-5 |
| spellingShingle | Zhen-Dong Zhong Ying-Yuan Xie Hong-Xuan Chen Ye-Lin Lan Xue-Hong Liu Jing-Yun Ji Fu Wu Lingmei Jin Jiekai Chen Daniel W. Mak Zhang Zhang Guan-Zheng Luo Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing Nature Communications |
| title | Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
| title_full | Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
| title_fullStr | Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
| title_full_unstemmed | Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
| title_short | Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
| title_sort | systematic comparison of tools used for m6a mapping from nanopore direct rna sequencing |
| url | https://doi.org/10.1038/s41467-023-37596-5 |
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