Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles

The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease. Ethylcyanoacrylate nanoparticles acted as the delivery system into cells. As the obligate repl...

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Bibliographic Details
Main Authors:	GITTITH SÁNCHEZ, DANIELA CUELLAR, INES ZULANTAY, MARTA GAJARDO, GUILLERMO GONZÁLEZ-MARTIN
Format:	Article
Language:	English
Published:	BMC 2002-01-01
Series:	Biological Research
Subjects:	nifurtimox nanoparticles amastigotes trypomastigotes Trypanosoma cruzi
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000100007

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