Automated quantification of levels of breast terminal duct lobular (TDLU) involution using deep learning
Abstract Convolutional neural networks (CNNs) offer the potential to generate comprehensive quantitative analysis of histologic features. Diagnostic reporting of benign breast disease (BBD) biopsies is usually limited to subjective assessment of the most severe lesion in a sample, while ignoring the...
Main Authors: | Thomas de Bel, Geert Litjens, Joshua Ogony, Melody Stallings-Mann, Jodi M. Carter, Tracy Hilton, Derek C. Radisky, Robert A. Vierkant, Brendan Broderick, Tanya L. Hoskin, Stacey J. Winham, Marlene H. Frost, Daniel W. Visscher, Teresa Allers, Amy C. Degnim, Mark E. Sherman, Jeroen A. W. M. van der Laak |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
|
Series: | npj Breast Cancer |
Online Access: | https://doi.org/10.1038/s41523-021-00378-7 |
Similar Items
-
396 Unraveling the Immunological Basis of Lobular Involution in Breast Cancer Development
by: Jaida Lue, et al.
Published: (2024-04-01) -
356 Upregulated Genes in Age-Related Lobular Involution Stagnation Represent Potential Biomarkers That Link To Increased Breast Cancer Risk
by: Derek Radisky, et al.
Published: (2023-04-01) -
Towards defining morphologic parameters of normal parous and nulliparous breast tissues by artificial intelligence
by: Joshua Ogony, et al.
Published: (2022-07-01) -
Associations between quantitative measures of TDLU involution and breast tumor molecular subtypes among breast cancer cases in the Black Women’s Health Study: a case–case analysis
by: Brittny C. Davis Lynn, et al.
Published: (2022-12-01) -
424 Deciphering the Immune Landscape in Benign Breast Disease: Implications for Risk Stratification and Breast Cancer Prevention
by: Matilde Rossi, et al.
Published: (2024-04-01)