Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague–Dawley rats

Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague–Dawley rats

Abstract Background Excitotoxicity-induced in vivo injury models are vital to reflect the pathophysiological features of acute spinal cord injury (SCI) in humans. The duration and concentration of chemical treatment controls the extent of neuronal cell damage. The extent of injury is explained in re...

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Bibliographic Details
Main Authors: Anam Anjum, Yt Jun Cheah, Muhammad Da’in Yazid, Muhammad Fauzi Daud, Jalilah Idris, Min Hwei Ng, Amaramalar Selvi Naicker, Ohnmar Htwe Ismail, Ramesh Kumar Athi Kumar, Geok Chin Tan, Yin Ping Wong, Mohd Kaisan Mahadi, Yogeswaran Lokanathan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Biological Research
Subjects:
Spinal cord injury (SCI)
Kainic acid
Locomotion
Motor neuron
Intra-spinal injection
Online Access:https://doi.org/10.1186/s40659-022-00407-0

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