Dengue overview: An updated systemic review
Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed. A syst...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Journal of Infection and Public Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034123002587 |
| _version_ | 1797690233283674112 |
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| author | Muhammad Bilal Khan Zih-Syuan Yang Chih-Yen Lin Ming-Cheng Hsu Aspiro Nayim Urbina Wanchai Assavalapsakul Wen-Hung Wang Yen-Hsu Chen Sheng-Fan Wang |
| author_facet | Muhammad Bilal Khan Zih-Syuan Yang Chih-Yen Lin Ming-Cheng Hsu Aspiro Nayim Urbina Wanchai Assavalapsakul Wen-Hung Wang Yen-Hsu Chen Sheng-Fan Wang |
| author_sort | Muhammad Bilal Khan |
| collection | DOAJ |
| description | Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed. A systemic literature review was conducted according to PRISMA guidelines to select proper references to give an overview of DENV infection. Results indicate that understanding the virus characteristics and epidemiology are essential to gain the basic and clinical knowledge as well as dengue disseminated pattern and status. Different factors and mechanisms are thought to be involved in the presentation of DHF and DSS, including antibody-dependent enhancement, immune dysregulation, viral virulence, host genetic susceptibility, and preexisting dengue antibodies. This study suggests that dissecting pathogenesis and risk factors as well as developing different types of therapeutic and control strategies against DENV infection are urgently needed. |
| first_indexed | 2024-03-12T01:56:36Z |
| format | Article |
| id | doaj.art-da822449ff874de39801a4179de76356 |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-03-12T01:56:36Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-da822449ff874de39801a4179de763562023-09-08T04:33:07ZengElsevierJournal of Infection and Public Health1876-03412023-10-01161016251642Dengue overview: An updated systemic reviewMuhammad Bilal Khan0Zih-Syuan Yang1Chih-Yen Lin2Ming-Cheng Hsu3Aspiro Nayim Urbina4Wanchai Assavalapsakul5Wen-Hung Wang6Yen-Hsu Chen7Sheng-Fan Wang8Center for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, TaiwanDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, ThailandSchool of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 804201, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan; Division of Infectious Disease, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 80708, TaiwanCenter for Tropical Medicine and Infectious Disease Research, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan; Corresponding author at: Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed. A systemic literature review was conducted according to PRISMA guidelines to select proper references to give an overview of DENV infection. Results indicate that understanding the virus characteristics and epidemiology are essential to gain the basic and clinical knowledge as well as dengue disseminated pattern and status. Different factors and mechanisms are thought to be involved in the presentation of DHF and DSS, including antibody-dependent enhancement, immune dysregulation, viral virulence, host genetic susceptibility, and preexisting dengue antibodies. This study suggests that dissecting pathogenesis and risk factors as well as developing different types of therapeutic and control strategies against DENV infection are urgently needed.http://www.sciencedirect.com/science/article/pii/S1876034123002587Dengue virusDengue feverDengue hemorrhagic feverDengue shock syndromeSystemic reviewPRISMA |
| spellingShingle | Muhammad Bilal Khan Zih-Syuan Yang Chih-Yen Lin Ming-Cheng Hsu Aspiro Nayim Urbina Wanchai Assavalapsakul Wen-Hung Wang Yen-Hsu Chen Sheng-Fan Wang Dengue overview: An updated systemic review Journal of Infection and Public Health Dengue virus Dengue fever Dengue hemorrhagic fever Dengue shock syndrome Systemic review PRISMA |
| title | Dengue overview: An updated systemic review |
| title_full | Dengue overview: An updated systemic review |
| title_fullStr | Dengue overview: An updated systemic review |
| title_full_unstemmed | Dengue overview: An updated systemic review |
| title_short | Dengue overview: An updated systemic review |
| title_sort | dengue overview an updated systemic review |
| topic | Dengue virus Dengue fever Dengue hemorrhagic fever Dengue shock syndrome Systemic review PRISMA |
| url | http://www.sciencedirect.com/science/article/pii/S1876034123002587 |
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