Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review)
Histiocytic tumors are a highly heterogeneous group of diseases, with Langerhans cell histiocytosis occupying the main place among it. Despite the rare frequency of occurrence, long-term analysis of clinical, morpho-immunological and molecular-biological features has allowed the development of effec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2022-01-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/519 |
| _version_ | 1826557119868960768 |
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| author | T. T. Valiev O. D. Gurieva A. I. Pavlovskaya |
| author_facet | T. T. Valiev O. D. Gurieva A. I. Pavlovskaya |
| author_sort | T. T. Valiev |
| collection | DOAJ |
| description | Histiocytic tumors are a highly heterogeneous group of diseases, with Langerhans cell histiocytosis occupying the main place among it. Despite the rare frequency of occurrence, long-term analysis of clinical, morpho-immunological and molecular-biological features has allowed the development of effective treatment protocols (especially in the pediatric cohort of patients). In addition to Langerhans cell histiocytosis, the histiocytic tumors group includes rare and casuistic variants, which include histiocytic sarcoma, Langerhans cell sarcoma, indeterminate dendritic cell tumor, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, and fibroblastic reticular cell tumor. The incidence of certain nosological variants is several cases per hundreds of millions of the population. Not surprisingly, the diagnostic criteria for this group of tumors need to be clarified, as do the therapeutic approaches. This review presents current data on rare histiocytic tumors, clinical features as well as morphological and immunobiological characteristics of the tumor substrate. The results of modern surgical and therapeutic treatment approaches are presented. |
| first_indexed | 2024-04-09T20:24:44Z |
| format | Article |
| id | doaj.art-da838e3b07b94304a77a413749a0ab62 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2025-03-14T08:23:32Z |
| publishDate | 2022-01-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-da838e3b07b94304a77a413749a0ab622025-03-02T13:07:13ZrusABV-pressОнкогематология1818-83462413-40232022-01-01171536410.17650/1818-8346-2022-17-1-53-64422Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review)T. T. Valiev0O. D. Gurieva1A. I. Pavlovskaya2N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaHistiocytic tumors are a highly heterogeneous group of diseases, with Langerhans cell histiocytosis occupying the main place among it. Despite the rare frequency of occurrence, long-term analysis of clinical, morpho-immunological and molecular-biological features has allowed the development of effective treatment protocols (especially in the pediatric cohort of patients). In addition to Langerhans cell histiocytosis, the histiocytic tumors group includes rare and casuistic variants, which include histiocytic sarcoma, Langerhans cell sarcoma, indeterminate dendritic cell tumor, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, and fibroblastic reticular cell tumor. The incidence of certain nosological variants is several cases per hundreds of millions of the population. Not surprisingly, the diagnostic criteria for this group of tumors need to be clarified, as do the therapeutic approaches. This review presents current data on rare histiocytic tumors, clinical features as well as morphological and immunobiological characteristics of the tumor substrate. The results of modern surgical and therapeutic treatment approaches are presented.https://oncohematology.abvpress.ru/ongm/article/view/519histiocytic sarcomalangerhans cell sarcomaindeterminate dendritic cell tumorinterdigitating dendritic cell sarcomafollicular dendritic cell sarcomafibroblastic reticular cell tumorclinical picturediagnosistreatment |
| spellingShingle | T. T. Valiev O. D. Gurieva A. I. Pavlovskaya Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) Онкогематология histiocytic sarcoma langerhans cell sarcoma indeterminate dendritic cell tumor interdigitating dendritic cell sarcoma follicular dendritic cell sarcoma fibroblastic reticular cell tumor clinical picture diagnosis treatment |
| title | Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) |
| title_full | Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) |
| title_fullStr | Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) |
| title_full_unstemmed | Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) |
| title_short | Rare variants of histiocytic tumors: peculiarities of diagnosis and choice of treatment (literature review) |
| title_sort | rare variants of histiocytic tumors peculiarities of diagnosis and choice of treatment literature review |
| topic | histiocytic sarcoma langerhans cell sarcoma indeterminate dendritic cell tumor interdigitating dendritic cell sarcoma follicular dendritic cell sarcoma fibroblastic reticular cell tumor clinical picture diagnosis treatment |
| url | https://oncohematology.abvpress.ru/ongm/article/view/519 |
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