Herpetic esophagitis following bendamustine-containing regimen
Hiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract:...
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Format: | Article |
Language: | English |
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Dove Medical Press
2016-06-01
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Series: | Therapeutics and Clinical Risk Management |
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Online Access: | https://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRM |
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author | Yamane H Monobe Y Tanikawa T Ochi N Honda Y Kawamoto H Takigawa N |
author_facet | Yamane H Monobe Y Tanikawa T Ochi N Honda Y Kawamoto H Takigawa N |
author_sort | Yamane H |
collection | DOAJ |
description | Hiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract: A 76-year-old Japanese woman presented to our hospital with anorexia. Two years before, she was diagnosed with non-Hodgkin’s lymphoma and had received ten cycles of systemic chemotherapy. After salvage chemotherapy with bendamustine and rituximab (B–R), bone marrow suppression had lasted >3 months. Esophagogastroscopy revealed polynesic white protrusions in the mid-esophagus. These lesions were diagnosed as herpetic esophagitis. To the best of our knowledge, there is no other report in which herpetic esophagitis has been documented as an adverse event of B–R regimen. Because the complication could cause symptomatic gastrointestinal discomfort, physicians should be aware of this disease. Keywords: bendamustine, herpetic esophagitis, immunodeficiency, non-Hodgkin’s lymphoma, rituximab |
first_indexed | 2024-12-18T23:47:49Z |
format | Article |
id | doaj.art-da83f9aff2ba4836866990360c63ac34 |
institution | Directory Open Access Journal |
issn | 1178-203X |
language | English |
last_indexed | 2024-12-18T23:47:49Z |
publishDate | 2016-06-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Therapeutics and Clinical Risk Management |
spelling | doaj.art-da83f9aff2ba4836866990360c63ac342022-12-21T20:47:09ZengDove Medical PressTherapeutics and Clinical Risk Management1178-203X2016-06-012016Issue 188388627254Herpetic esophagitis following bendamustine-containing regimenYamane HMonobe YTanikawa TOchi NHonda YKawamoto HTakigawa NHiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract: A 76-year-old Japanese woman presented to our hospital with anorexia. Two years before, she was diagnosed with non-Hodgkin’s lymphoma and had received ten cycles of systemic chemotherapy. After salvage chemotherapy with bendamustine and rituximab (B–R), bone marrow suppression had lasted >3 months. Esophagogastroscopy revealed polynesic white protrusions in the mid-esophagus. These lesions were diagnosed as herpetic esophagitis. To the best of our knowledge, there is no other report in which herpetic esophagitis has been documented as an adverse event of B–R regimen. Because the complication could cause symptomatic gastrointestinal discomfort, physicians should be aware of this disease. Keywords: bendamustine, herpetic esophagitis, immunodeficiency, non-Hodgkin’s lymphoma, rituximabhttps://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRMbendamustineherpetic esophagitisimmunodeficiencynon-Hodgkin's lymphomarituximab |
spellingShingle | Yamane H Monobe Y Tanikawa T Ochi N Honda Y Kawamoto H Takigawa N Herpetic esophagitis following bendamustine-containing regimen Therapeutics and Clinical Risk Management bendamustine herpetic esophagitis immunodeficiency non-Hodgkin's lymphoma rituximab |
title | Herpetic esophagitis following bendamustine-containing regimen |
title_full | Herpetic esophagitis following bendamustine-containing regimen |
title_fullStr | Herpetic esophagitis following bendamustine-containing regimen |
title_full_unstemmed | Herpetic esophagitis following bendamustine-containing regimen |
title_short | Herpetic esophagitis following bendamustine-containing regimen |
title_sort | herpetic esophagitis following bendamustine containing regimen |
topic | bendamustine herpetic esophagitis immunodeficiency non-Hodgkin's lymphoma rituximab |
url | https://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRM |
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