Herpetic esophagitis following bendamustine-containing regimen

Hiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract:...

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Main Authors: Yamane H, Monobe Y, Tanikawa T, Ochi N, Honda Y, Kawamoto H, Takigawa N
Format: Article
Language:English
Published: Dove Medical Press 2016-06-01
Series:Therapeutics and Clinical Risk Management
Subjects:
Online Access:https://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRM
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author Yamane H
Monobe Y
Tanikawa T
Ochi N
Honda Y
Kawamoto H
Takigawa N
author_facet Yamane H
Monobe Y
Tanikawa T
Ochi N
Honda Y
Kawamoto H
Takigawa N
author_sort Yamane H
collection DOAJ
description Hiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract: A 76-year-old Japanese woman presented to our hospital with anorexia. Two years before, she was diagnosed with non-Hodgkin’s lymphoma and had received ten cycles of systemic chemotherapy. After salvage chemotherapy with bendamustine and rituximab (B–R), bone marrow suppression had lasted >3 months. Esophagogastroscopy revealed polynesic white protrusions in the mid-esophagus. These lesions were diagnosed as herpetic esophagitis. To the best of our knowledge, there is no other report in which herpetic esophagitis has been documented as an adverse event of B–R regimen. Because the complication could cause symptomatic gastrointestinal discomfort, physicians should be aware of this disease. Keywords: bendamustine, herpetic esophagitis, immunodeficiency, non-Hodgkin’s lymphoma, rituximab
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spelling doaj.art-da83f9aff2ba4836866990360c63ac342022-12-21T20:47:09ZengDove Medical PressTherapeutics and Clinical Risk Management1178-203X2016-06-012016Issue 188388627254Herpetic esophagitis following bendamustine-containing regimenYamane HMonobe YTanikawa TOchi NHonda YKawamoto HTakigawa NHiromichi Yamane,1 Yasumasa Monobe,2 Tomohiro Tanikawa,3 Nobuaki Ochi,1 Yoshihiro Honda,1 Hirofumi Kawamoto,3 Nagio Takigawa1 1Department of General Internal Medicine 4, 2Department of Pathology, 3Department of General Internal Medicine 2, Kawasaki Medical School, Kita-ku, Okayama, Japan Abstract: A 76-year-old Japanese woman presented to our hospital with anorexia. Two years before, she was diagnosed with non-Hodgkin’s lymphoma and had received ten cycles of systemic chemotherapy. After salvage chemotherapy with bendamustine and rituximab (B–R), bone marrow suppression had lasted >3 months. Esophagogastroscopy revealed polynesic white protrusions in the mid-esophagus. These lesions were diagnosed as herpetic esophagitis. To the best of our knowledge, there is no other report in which herpetic esophagitis has been documented as an adverse event of B–R regimen. Because the complication could cause symptomatic gastrointestinal discomfort, physicians should be aware of this disease. Keywords: bendamustine, herpetic esophagitis, immunodeficiency, non-Hodgkin’s lymphoma, rituximabhttps://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRMbendamustineherpetic esophagitisimmunodeficiencynon-Hodgkin's lymphomarituximab
spellingShingle Yamane H
Monobe Y
Tanikawa T
Ochi N
Honda Y
Kawamoto H
Takigawa N
Herpetic esophagitis following bendamustine-containing regimen
Therapeutics and Clinical Risk Management
bendamustine
herpetic esophagitis
immunodeficiency
non-Hodgkin's lymphoma
rituximab
title Herpetic esophagitis following bendamustine-containing regimen
title_full Herpetic esophagitis following bendamustine-containing regimen
title_fullStr Herpetic esophagitis following bendamustine-containing regimen
title_full_unstemmed Herpetic esophagitis following bendamustine-containing regimen
title_short Herpetic esophagitis following bendamustine-containing regimen
title_sort herpetic esophagitis following bendamustine containing regimen
topic bendamustine
herpetic esophagitis
immunodeficiency
non-Hodgkin's lymphoma
rituximab
url https://www.dovepress.com/herpetic-esophagitis-following-bendamustine-containing-regimen-peer-reviewed-article-TCRM
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AT ochin herpeticesophagitisfollowingbendamustinecontainingregimen
AT honday herpeticesophagitisfollowingbendamustinecontainingregimen
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