Functional crosstalk between the cohesin loader and chromatin remodelers
Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-35444-6 |
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author | Sofía Muñoz Andrew Jones Céline Bouchoux Tegan Gilmore Harshil Patel Frank Uhlmann |
author_facet | Sofía Muñoz Andrew Jones Céline Bouchoux Tegan Gilmore Harshil Patel Frank Uhlmann |
author_sort | Sofía Muñoz |
collection | DOAJ |
description | Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes |
first_indexed | 2024-04-11T12:34:56Z |
format | Article |
id | doaj.art-da865112279a4948a1a8847c28f404a2 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-11T12:34:56Z |
publishDate | 2022-12-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-da865112279a4948a1a8847c28f404a22022-12-22T04:23:39ZengNature PortfolioNature Communications2041-17232022-12-0113111210.1038/s41467-022-35444-6Functional crosstalk between the cohesin loader and chromatin remodelersSofía Muñoz0Andrew Jones1Céline Bouchoux2Tegan Gilmore3Harshil Patel4Frank Uhlmann5Chromosome Segregation Laboratory, The Francis Crick InstituteProteomics Science Technology Platform, The Francis Crick InstituteChromosome Segregation Laboratory, The Francis Crick InstituteBioinformatics & Biostatistics Science Technology Platform, The Francis Crick InstituteBioinformatics & Biostatistics Science Technology Platform, The Francis Crick InstituteChromosome Segregation Laboratory, The Francis Crick InstituteChromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomeshttps://doi.org/10.1038/s41467-022-35444-6 |
spellingShingle | Sofía Muñoz Andrew Jones Céline Bouchoux Tegan Gilmore Harshil Patel Frank Uhlmann Functional crosstalk between the cohesin loader and chromatin remodelers Nature Communications |
title | Functional crosstalk between the cohesin loader and chromatin remodelers |
title_full | Functional crosstalk between the cohesin loader and chromatin remodelers |
title_fullStr | Functional crosstalk between the cohesin loader and chromatin remodelers |
title_full_unstemmed | Functional crosstalk between the cohesin loader and chromatin remodelers |
title_short | Functional crosstalk between the cohesin loader and chromatin remodelers |
title_sort | functional crosstalk between the cohesin loader and chromatin remodelers |
url | https://doi.org/10.1038/s41467-022-35444-6 |
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