Functional crosstalk between the cohesin loader and chromatin remodelers

Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes

Bibliographic Details
Main Authors: Sofía Muñoz, Andrew Jones, Céline Bouchoux, Tegan Gilmore, Harshil Patel, Frank Uhlmann
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35444-6
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author Sofía Muñoz
Andrew Jones
Céline Bouchoux
Tegan Gilmore
Harshil Patel
Frank Uhlmann
author_facet Sofía Muñoz
Andrew Jones
Céline Bouchoux
Tegan Gilmore
Harshil Patel
Frank Uhlmann
author_sort Sofía Muñoz
collection DOAJ
description Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomes
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language English
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spelling doaj.art-da865112279a4948a1a8847c28f404a22022-12-22T04:23:39ZengNature PortfolioNature Communications2041-17232022-12-0113111210.1038/s41467-022-35444-6Functional crosstalk between the cohesin loader and chromatin remodelersSofía Muñoz0Andrew Jones1Céline Bouchoux2Tegan Gilmore3Harshil Patel4Frank Uhlmann5Chromosome Segregation Laboratory, The Francis Crick InstituteProteomics Science Technology Platform, The Francis Crick InstituteChromosome Segregation Laboratory, The Francis Crick InstituteBioinformatics & Biostatistics Science Technology Platform, The Francis Crick InstituteBioinformatics & Biostatistics Science Technology Platform, The Francis Crick InstituteChromosome Segregation Laboratory, The Francis Crick InstituteChromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear nucleosomeshttps://doi.org/10.1038/s41467-022-35444-6
spellingShingle Sofía Muñoz
Andrew Jones
Céline Bouchoux
Tegan Gilmore
Harshil Patel
Frank Uhlmann
Functional crosstalk between the cohesin loader and chromatin remodelers
Nature Communications
title Functional crosstalk between the cohesin loader and chromatin remodelers
title_full Functional crosstalk between the cohesin loader and chromatin remodelers
title_fullStr Functional crosstalk between the cohesin loader and chromatin remodelers
title_full_unstemmed Functional crosstalk between the cohesin loader and chromatin remodelers
title_short Functional crosstalk between the cohesin loader and chromatin remodelers
title_sort functional crosstalk between the cohesin loader and chromatin remodelers
url https://doi.org/10.1038/s41467-022-35444-6
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