Analysis of Corneal Distortion after Myopic PRK

The purpose of the study is to evaluate the corneal biomechanical properties (CBP) and their behaviors after myopic refractive surgery both with Ocular Response Analyzer (ORA) and Corvis ST (CST). This retrospective study included 145 eyes of 145 patients with a mean age of 33.13 ± 9.24 years, who u...

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Main Authors: Michele Lanza, Luigi De Rosa, Sandro Sbordone, Rosa Boccia, Ugo Antonello Gironi Carnevale, Francesca Simonelli
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/1/82
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author Michele Lanza
Luigi De Rosa
Sandro Sbordone
Rosa Boccia
Ugo Antonello Gironi Carnevale
Francesca Simonelli
author_facet Michele Lanza
Luigi De Rosa
Sandro Sbordone
Rosa Boccia
Ugo Antonello Gironi Carnevale
Francesca Simonelli
author_sort Michele Lanza
collection DOAJ
description The purpose of the study is to evaluate the corneal biomechanical properties (CBP) and their behaviors after myopic refractive surgery both with Ocular Response Analyzer (ORA) and Corvis ST (CST). This retrospective study included 145 eyes of 145 patients with a mean age of 33.13 ± 9.24 years, who underwent myopic photorefractive keratectomy (PRK) for a refractive defect, measured as spherical equivalent, of mean −4.69 ± 2.04 D and have been evaluated before surgery and at 1, 3 and 6 months follow-up. Corneal hysteresis (CH) and corneal resistance factor (CRF) values significantly decreased after 1 month and remained statistically stable during further follow-ups. CST parameters had a different evolution: only second applanation time (AT2) differences showed a significant variation after 1 month that did not statistically change over time. Highest concavity deformation amplitude (HCDA), highest concavity peak distance (HCPD), first applanation time (AT1) and velocity (AV1) showed continuous significant differences both after 3 and after 6 months. This study suggests that after central surface ablation surgery, such as myopic PRK, corneal shape is remodeling, and its deformation parameters are going to change even at 6 months follow-up. This indicates that it should be important to evaluate refractive surgery patients during a longer follow-up because this could allow earlier diagnosis and better management of late-onset complications.
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spelling doaj.art-da8e1708113b4baea73d6180e3f858c22023-11-21T02:52:18ZengMDPI AGJournal of Clinical Medicine2077-03832020-12-011018210.3390/jcm10010082Analysis of Corneal Distortion after Myopic PRKMichele Lanza0Luigi De Rosa1Sandro Sbordone2Rosa Boccia3Ugo Antonello Gironi Carnevale4Francesca Simonelli5Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyMultidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 80132 Napoli, ItalyThe purpose of the study is to evaluate the corneal biomechanical properties (CBP) and their behaviors after myopic refractive surgery both with Ocular Response Analyzer (ORA) and Corvis ST (CST). This retrospective study included 145 eyes of 145 patients with a mean age of 33.13 ± 9.24 years, who underwent myopic photorefractive keratectomy (PRK) for a refractive defect, measured as spherical equivalent, of mean −4.69 ± 2.04 D and have been evaluated before surgery and at 1, 3 and 6 months follow-up. Corneal hysteresis (CH) and corneal resistance factor (CRF) values significantly decreased after 1 month and remained statistically stable during further follow-ups. CST parameters had a different evolution: only second applanation time (AT2) differences showed a significant variation after 1 month that did not statistically change over time. Highest concavity deformation amplitude (HCDA), highest concavity peak distance (HCPD), first applanation time (AT1) and velocity (AV1) showed continuous significant differences both after 3 and after 6 months. This study suggests that after central surface ablation surgery, such as myopic PRK, corneal shape is remodeling, and its deformation parameters are going to change even at 6 months follow-up. This indicates that it should be important to evaluate refractive surgery patients during a longer follow-up because this could allow earlier diagnosis and better management of late-onset complications.https://www.mdpi.com/2077-0383/10/1/82myopic PRKcorneal deformationcorneal biomechanical propertiesORACorvis ST
spellingShingle Michele Lanza
Luigi De Rosa
Sandro Sbordone
Rosa Boccia
Ugo Antonello Gironi Carnevale
Francesca Simonelli
Analysis of Corneal Distortion after Myopic PRK
Journal of Clinical Medicine
myopic PRK
corneal deformation
corneal biomechanical properties
ORA
Corvis ST
title Analysis of Corneal Distortion after Myopic PRK
title_full Analysis of Corneal Distortion after Myopic PRK
title_fullStr Analysis of Corneal Distortion after Myopic PRK
title_full_unstemmed Analysis of Corneal Distortion after Myopic PRK
title_short Analysis of Corneal Distortion after Myopic PRK
title_sort analysis of corneal distortion after myopic prk
topic myopic PRK
corneal deformation
corneal biomechanical properties
ORA
Corvis ST
url https://www.mdpi.com/2077-0383/10/1/82
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