Recent update on the management of anaphylaxis
Anaphylaxis is a life-threatening systemic allergic reaction presenting various clinical manifestations. Its prevalence has increased in almost all age groups and both sexes. Food, venom, and drugs are major causes in both children and adults; a higher prevalence of food-induced anaphylaxis is noted...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Emergency Medicine
2021-09-01
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| Series: | Clinical and Experimental Emergency Medicine |
| Subjects: | |
| Online Access: | http://ceemjournal.org/upload/pdf/ceem-21-121.pdf |
| _version_ | 1797897187178315776 |
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| author | Quang Luu Quoc Tra Cao Thi Bich Jae-Hyuk Jang Hae-Sim Park |
| author_facet | Quang Luu Quoc Tra Cao Thi Bich Jae-Hyuk Jang Hae-Sim Park |
| author_sort | Quang Luu Quoc |
| collection | DOAJ |
| description | Anaphylaxis is a life-threatening systemic allergic reaction presenting various clinical manifestations. Its prevalence has increased in almost all age groups and both sexes. Food, venom, and drugs are major causes in both children and adults; a higher prevalence of food-induced anaphylaxis is noted in children, while a higher prevalence of drug-induced anaphylaxis is noted in adults. The pathogenic mechanism is mediated by immunologic and nonimmunologic mechanisms, where mast cells and basophils are key cells that release mediators. A diagnosis of anaphylaxis is mainly based on clinical symptoms and physical findings; however, an increased serum tryptase level is a useful biomarker. Epinephrine is the first-line drug to treat acute symptoms, and an epinephrine auto-injector should be prescribed for each patient. Antihistamines and systemic corticosteroids are used to relieve symptoms. This review updates current issues in the management of anaphylaxis as well as the new guidelines for proper diagnosis and treatment. |
| first_indexed | 2024-04-10T07:53:35Z |
| format | Article |
| id | doaj.art-da8f1979348f461bb2b55c23dfe5af75 |
| institution | Directory Open Access Journal |
| issn | 2383-4625 |
| language | English |
| last_indexed | 2024-04-10T07:53:35Z |
| publishDate | 2021-09-01 |
| publisher | The Korean Society of Emergency Medicine |
| record_format | Article |
| series | Clinical and Experimental Emergency Medicine |
| spelling | doaj.art-da8f1979348f461bb2b55c23dfe5af752023-02-23T07:05:38ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252021-09-018316017210.15441/ceem.21.121343Recent update on the management of anaphylaxisQuang Luu Quoc0Tra Cao Thi Bich1Jae-Hyuk Jang2Hae-Sim Park3 Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, KoreaAnaphylaxis is a life-threatening systemic allergic reaction presenting various clinical manifestations. Its prevalence has increased in almost all age groups and both sexes. Food, venom, and drugs are major causes in both children and adults; a higher prevalence of food-induced anaphylaxis is noted in children, while a higher prevalence of drug-induced anaphylaxis is noted in adults. The pathogenic mechanism is mediated by immunologic and nonimmunologic mechanisms, where mast cells and basophils are key cells that release mediators. A diagnosis of anaphylaxis is mainly based on clinical symptoms and physical findings; however, an increased serum tryptase level is a useful biomarker. Epinephrine is the first-line drug to treat acute symptoms, and an epinephrine auto-injector should be prescribed for each patient. Antihistamines and systemic corticosteroids are used to relieve symptoms. This review updates current issues in the management of anaphylaxis as well as the new guidelines for proper diagnosis and treatment.http://ceemjournal.org/upload/pdf/ceem-21-121.pdfanaphylaxisbiomarkersdiagnosisepinephrinetherapeutics |
| spellingShingle | Quang Luu Quoc Tra Cao Thi Bich Jae-Hyuk Jang Hae-Sim Park Recent update on the management of anaphylaxis Clinical and Experimental Emergency Medicine anaphylaxis biomarkers diagnosis epinephrine therapeutics |
| title | Recent update on the management of anaphylaxis |
| title_full | Recent update on the management of anaphylaxis |
| title_fullStr | Recent update on the management of anaphylaxis |
| title_full_unstemmed | Recent update on the management of anaphylaxis |
| title_short | Recent update on the management of anaphylaxis |
| title_sort | recent update on the management of anaphylaxis |
| topic | anaphylaxis biomarkers diagnosis epinephrine therapeutics |
| url | http://ceemjournal.org/upload/pdf/ceem-21-121.pdf |
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