The physiology of foamy phagocytes in multiple sclerosis

The physiology of foamy phagocytes in multiple sclerosis

Abstract Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by massive infiltration of immune cells, demyelination, and axonal loss. Active MS lesions mainly consist of macrophages and microglia containing abundant intracellular myelin remnants. Initial studies...

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Bibliographic Details
Main Authors: Elien Grajchen, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Acta Neuropathologica Communications
Subjects:
Macrophage
Microglia
Polarization
Neuroinflammation
Remyelination
Multiple sclerosis
Online Access:http://link.springer.com/article/10.1186/s40478-018-0628-8

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