Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram
Abstract Background The main objective of this study was to investigate the risk factors for recollapse of new vertebral compression fractures (NVCFs) after percutaneous kyphoplasty (PKP) treatment for osteoporotic vertebral compression fracture (OVCF) and to construct a new nomogram model. Methods...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-022-05409-3 |
| _version_ | 1818203691475271680 |
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| author | FuCheng Bian GuangYu Bian Li Zhao Shuo Huang JinHui Fang YongSheng An |
| author_facet | FuCheng Bian GuangYu Bian Li Zhao Shuo Huang JinHui Fang YongSheng An |
| author_sort | FuCheng Bian |
| collection | DOAJ |
| description | Abstract Background The main objective of this study was to investigate the risk factors for recollapse of new vertebral compression fractures (NVCFs) after percutaneous kyphoplasty (PKP) treatment for osteoporotic vertebral compression fracture (OVCF) and to construct a new nomogram model. Methods We retrospectively analysed single-level OVCFs from January 2017 to June 2020, randomizing patients to a training set and a testing set. In the training set, independent risk factors for NVCFs in OVCF patients treated with PKP were obtained by univariate and multivariate regression analyses. These risk factors were then used as the basis for constructing a nomogram model. Finally, internal validation of the built model was performed in the testing set using the consistency index (C-index), receiver operating characteristic (ROC) curves, calibration curves and decision curve analysis (DCA). Results In total, 371 patients were included in this study. NVCFs occurred in 21.7% of the training set patients, and multivariate regression analysis showed that a low Hounsfield unit (HU) value, cement leakage, and thoracolumbar (TL) junction fracture were independent risk factors for NVCF after PKP. The C-index was 0.81 (95% CI: 0.74–0.81), and the validation showed that the predicted values of the established model were in good agreement with the actual values. Conclusions In this study, three independent risk factors were obtained by regression analysis. A nomogram model was constructed to guide clinical work and to make clinical decisions relatively accurately to prevent the occurrence of vertebral recollapse fractures. |
| first_indexed | 2024-12-12T03:29:22Z |
| format | Article |
| id | doaj.art-da915ee1ba714fed95233de0161067de |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-12T03:29:22Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-da915ee1ba714fed95233de0161067de2022-12-22T00:39:57ZengBMCBMC Musculoskeletal Disorders1471-24742022-05-012311910.1186/s12891-022-05409-3Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogramFuCheng Bian0GuangYu Bian1Li Zhao2Shuo Huang3JinHui Fang4YongSheng An5Department of Endoscopic Diagnosis, Daqing Oilfield General HospitalDepartment of Obstetrics, Daqing Oilfield General HospitalDepartment of Cardiac Surgery, Nanfang Hospital of Southern Medical UniversityDepartment of Marketing and Tourism, Northeast Petroleum UniversityDepartment of Endoscopic Diagnosis, Daqing Oilfield General HospitalDepartment of Orthopaedic, Chengde Medical University Affiliated HospitalAbstract Background The main objective of this study was to investigate the risk factors for recollapse of new vertebral compression fractures (NVCFs) after percutaneous kyphoplasty (PKP) treatment for osteoporotic vertebral compression fracture (OVCF) and to construct a new nomogram model. Methods We retrospectively analysed single-level OVCFs from January 2017 to June 2020, randomizing patients to a training set and a testing set. In the training set, independent risk factors for NVCFs in OVCF patients treated with PKP were obtained by univariate and multivariate regression analyses. These risk factors were then used as the basis for constructing a nomogram model. Finally, internal validation of the built model was performed in the testing set using the consistency index (C-index), receiver operating characteristic (ROC) curves, calibration curves and decision curve analysis (DCA). Results In total, 371 patients were included in this study. NVCFs occurred in 21.7% of the training set patients, and multivariate regression analysis showed that a low Hounsfield unit (HU) value, cement leakage, and thoracolumbar (TL) junction fracture were independent risk factors for NVCF after PKP. The C-index was 0.81 (95% CI: 0.74–0.81), and the validation showed that the predicted values of the established model were in good agreement with the actual values. Conclusions In this study, three independent risk factors were obtained by regression analysis. A nomogram model was constructed to guide clinical work and to make clinical decisions relatively accurately to prevent the occurrence of vertebral recollapse fractures.https://doi.org/10.1186/s12891-022-05409-3Osteoporotic vertebral compression fracturePercutaneous kyphoplastyRisk factorNomogram |
| spellingShingle | FuCheng Bian GuangYu Bian Li Zhao Shuo Huang JinHui Fang YongSheng An Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram BMC Musculoskeletal Disorders Osteoporotic vertebral compression fracture Percutaneous kyphoplasty Risk factor Nomogram |
| title | Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram |
| title_full | Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram |
| title_fullStr | Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram |
| title_full_unstemmed | Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram |
| title_short | Risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients: establishment of a nomogram |
| title_sort | risk factors for recollapse of new vertebral compression fractures after percutaneous kyphoplasty in geriatric patients establishment of a nomogram |
| topic | Osteoporotic vertebral compression fracture Percutaneous kyphoplasty Risk factor Nomogram |
| url | https://doi.org/10.1186/s12891-022-05409-3 |
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